“…The IIS pathway regulates metabolism, growth, and life span by detecting nutrient levels. Studies conducted on IIS pathway suggested an inverse correlation between IIS pathway activation and life span extension (Zulkefli, Shuid, & Aan, 2020). Similarly, the attenuation of mTOR signalling pathway, which regulates cell survival and growth, also contributes to life span extension in model organisms (Antikainen, Driscoll, Haspel, & Dobrowolski, 2017).…”