1991
DOI: 10.1159/000473629
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Role of Inhibitor Deficiency in Urolithiasis

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Cited by 29 publications
(4 citation statements)
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“…In short, while some authors found no difference at all [7][8][9][10]. Others claimed that stone formers have a lower GAG excretion [II.…”
Section: Introductionmentioning
confidence: 99%
“…In short, while some authors found no difference at all [7][8][9][10]. Others claimed that stone formers have a lower GAG excretion [II.…”
Section: Introductionmentioning
confidence: 99%
“…Lithogenic protection in children’s urine is higher compared with adults due to a higher excretion of macromolecules, including increased excretion of Cit, GAG and fibronectin [ 2 , 4 , 43 , 44 ]. Elevated GAGs excretion in infants and toddlers’ urine is explained by increased excretion of proteoglycans in longitudinally growing bones [ 43 ]. This protective role of GAGs is consistent with observation for the lowest incidence of urinary stone formation in children 0–3 years [ 45 ].…”
Section: Discussionmentioning
confidence: 99%
“…This protective role of GAGs is consistent with observation for the lowest incidence of urinary stone formation in children 0–3 years [ 45 ]. Articles describing excretion of GAGs in urine are scarce and with no clear consensus [ 16 , 42 , 43 , 44 , 46 ]. Reduced excretion of GAGs’ in urine is rarely reported in children [ 15 , 42 , 44 , 46 ].…”
Section: Discussionmentioning
confidence: 99%
“…We have not mentioned macromolecular promoters and inhibitors or the concept of inhibitory macromolecule deficiency, but routine determination of such substances is impractical (90)(91)(92)(93)(94). In the future, macromolecular factors may eventually be incorporated in the Equil2 program.…”
Section: Discussionmentioning
confidence: 99%