Role of Infrainguinal Angioplasty in the Treatment of Critical Limb Ischaemia

Eskelinen, E; Lepäntalo, Mauri

doi:10.1177/145749690709600103

Cited by 12 publications

(13 citation statements)

References 45 publications

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“…The current study shows a high peri-operative mortality rate for major amputations of the lower limbs due to critical ischemia [3,4]. One aspect that highlights the severity of the disease is the internationally published data on mortality rates that report deaths in between 72% and 92% of the cases within the first 6 to 8 years of follow up [5,7].…”

Section: Discussionmentioning

confidence: 77%

“…The most important risk factors for the development of critical ischemia of the legs are diabetes, smoking, arterial hypertension, lipid alterations, obesity and low blood pressure in the ankles [1][2][3]. Without therapy using medications or interventions, around 40% of these individuals loose their legs in less than 6 months and 20% die [2].…”

Section: Introductionmentioning

confidence: 99%

“…One study evaluated 2 random perspective trials comparing bypass surgery and angioplasty and found no significant difference in the amputation rates between the surgery and infrainguinal angioplasty groups; however these procedures were employed in only 15% of the patients with severe ischemia [3].…”

Section: Introductionmentioning

confidence: 99%

“…Of 150,000 amputations annually in the United States of America, peri-operative death occurred in 5% to 10% of the cases in which amputation was below the knee, increasing to 50% for amputations above the knee due to comorbidities [3]. Another study reported a peri-operative mortality rate of 15.7% [4].…”

Section: Introductionmentioning

confidence: 99%

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Hospital Mortality After Major Amputation of the Lower Limbs for Critical Ischemia

Godoy¹,

Ribeiro²,

Caracanhas³

2009

TOATHERTJ

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Abstract:The prevalence of major amputations of lower limbs increases as the population ages. The aim of the current study was to evaluate hospital death in cases of major amputations for critical limb ischemia in a teaching hospital.Hospital mortality during the peri-operative period was evaluated in 231 major amputations of legs due to critical limb ischemia between January 2005 and 2007. Thirty-six (15.6%) deaths occurred in this period, 14 women and 22 men (ages between 47 and 86). Of these patients, 13 (5.6%) died during the first hospitalization and 23 (9.9%) during rehospitalizations within the first month.High death rates were observed in the peri-operative period of major amputations of the lower limbs due to critical limb ischemia.

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Section: Discussionmentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Hospital Mortality After Major Amputation of the Lower Limbs for Critical Ischemia

Godoy¹,

Ribeiro²,

Caracanhas³

2009

TOATHERTJ

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“…The possibility of effectively revascularizing the patients with CLI did change the prognosis of this severe condition. 18,19…”

Section: Discussionmentioning

confidence: 99%

Outcomes of Three Years of Teamwork on Critical Limb Ischemia in Patients With Diabetes and Foot Lesions

Scatena

Petruzzi

Ferrari

et al. 2012

The International Journal of Lower Extremity Wounds

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To evaluate the outcomes of a multidisciplinary team working on diabetic foot (DF) patients with critical limb ischemia (CLI) in a specialized center, the authors retrospectively traced all the patients admitted in their department in 3 consecutive years with a diagnosis of CLI. From January 2006 to December 2008, 245 consecutive DF patients with CLI according the TransAtlantic interSociety Consensus II criteria were included in the study. Treatment strategy was decided by a team of diabetologists, inteventional radiologists, and vascular surgeons. Technical and clinical success, mortality, and ulcer recurrence were evaluated at 6 months and at a mean follow-up of 19.5 ± 13.4 months. Percutaneous transluminal angioplasty (PTA) was performed in 189 (77%) patients, whereas medical treatment, open surgical revascularization (OSR), and primary amputation were performed in 44 (18.3%), 11 (4.3%), and 1 (0.5%) patients, respectively. Revascularization was successful in 227/233 (97.4%) patients. At follow-up, the overall clinical success rate was 60.4%; it was significantly (P = .001) higher after revascularization (75.9%) compared with medical treatment (48.3%). During follow-up, surgical interventions in the foot were 1.5 ± 0.4 in those treated with PTA, 1.6 ± 0.5 in those treated with OSR, and 0.3 ± 0.8 in those receiving medical therapy (P < .05 compared with the others). Ulcer recurrence occurred in 29 (11.8%) patients: 4 (1.6%) in PTA, 2 (0.8%) in OSR, and 23 (9.4%) in the medical therapy group (P < .05). Major amputation rate was 9.3%, being significantly (P = .04) lower after revascularization (5.2%) compared with medical therapy alone (13.8%). Cumulative mortality rate was 10.6%. In conclusion, this study confirms the positive role of a PTA-first approach for revascularizing the complex cases of DF with CLI in a teamwork management strategy.

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Unterschenkelarterienverschlüsse (S2)

2010

Leitlinien Zu Diagnostik Und Therapie in Der Gefäßchirurgie

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Role of Infrainguinal Angioplasty in the Treatment of Critical Limb Ischaemia

Cited by 12 publications

References 45 publications

Hospital Mortality After Major Amputation of the Lower Limbs for Critical Ischemia

Hospital Mortality After Major Amputation of the Lower Limbs for Critical Ischemia

Outcomes of Three Years of Teamwork on Critical Limb Ischemia in Patients With Diabetes and Foot Lesions

Unterschenkelarterienverschlüsse (S2)

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