Role of inflammatory cytokines and the gut microbiome in vascular dementia: insights from Mendelian randomization analysis
Yihan Yang,
Ting Rao,
Sheng Wei
et al.
Abstract:BackgroundBoth inflammatory cytokines and the gut microbiome are susceptibility factors for vascular dementia (VaD). The trends in the overall changes in the dynamics of inflammatory cytokines and in the composition of the gut microbiome are influenced by a variety of factors, making it difficult to fully explain the different effects of both on the different subtypes of VaD. Therefore, this Mendelian randomization (MR) study identified the inflammatory cytokines and gut microbiome members that influence the r… Show more
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