Role of IL-33/ST2 Pathway in Inflammatory Bowel Disease: An Overview and Future Perspectives
Walter Giordano,
Gabriele Ricciardi,
Marco Casciaro
et al.
Abstract:Inflammatory bowel disease (IBD) represents a heterogenous and complex group of idiopathic chronic inflammatory conditions affecting the gastrointestinal tract and other extraintestinal systems with rising global incidences. The interplay of genetic predisposition and environmental factors contributes to its pathogenesis. Among the key cytokines implicated in IBD molecular alterations, IL-33 stands out for its multifaceted roles in both pathogenesis and repair mechanisms. IL-33, known for its action in initiat… Show more
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