Role of BicDR in bristle shaft construction and support of BicD functions
Aleksandra Jejina,
Yeniffer Ayala,
Dirk Beuchle
et al.
Abstract:Cell polarization requires asymmetric localization of numerous mRNAs, proteins, and organelles. The movement of cargo towards the minus end of microtubules mostly depends on cytoplasmic dynein motors. In the dynein/dynactin/Bicaudal-D transport machinery, Bicaudal-D (BicD) links the cargo to the motor. Here we focus on the role of Drosophila BicD-related (BicDR) in the development of the long bristles. Together with BicD, it contributes to the organization and stability of the actin cytoskeleton in the not-yet… Show more
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