Role of herbal, nutraceutical and synthetic agents in oligoasthenoteratozoospermia: A comparative assessment

Abstract

Subfertile males with idiopathic oligoasthenoteratozoospermia (iOAT) can experience a decrease in fertilization and conception rates. Natural antioxidant supplements and herbal treatments recognized to be effective in enhancing fertility. These have the potential to become one of the most efficient medications for treating male infertility. Our study emphasis at how these medication interventions improve several semen parameters while diminishing male factor infertility. A comprehensive literature search using PubMed, Embase, Scopus, Google Scholar and Science Direct were conducted to locate the research papers, focusing the usage of herbal and antioxidant therapies and their favourable effects on various semen parameters on reproductive health. Research based on <i>in vitro</i> and <i>in vivo</i> studies showed that antioxidants, herbal remedies and synthetic therapies have a substantial influence on various sperm parameter. The findings of randomized clinical trials and other preclinical data on exposure of numerous antioxidant supplements, herbal medicines and synthetic therapy demonstrated a considerable benefit to sperm parameters like sperm count, motility, morphology and fertilization rates. It is evident that herbal therapy and proper antioxidant supplementation can improve the rate of conception, so in contrary to synthetic medication, natural and antioxidant therapies are liable to provide better treatment options in managing male fecundity problems.