Role of Helicobacter pylori coccoid forms in infection and recrudescence

Sarem, Muhannad; Corti, Rodolfo

doi:10.1016/j.gastre.2015.12.005

Cited by 30 publications

(28 citation statements)

References 66 publications

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“…Among them, the coccoid form is divided into two subtypes. Type A has irregular edges with a rough surface and is considered to be a dead form, while type B has a smoother surface, is smaller and is considered to be a dormant form . A previous study has confirmed that coccoid H pylori exists in the stomach and duodenum, and the number in the duodenum is higher than that in the stomach.…”

Section: Influencing Factors Of H Pylori Recrudescencementioning

confidence: 96%

“…Helicobacter pylori recurrence is generally divided into recrudescence and reinfection . Recrudescence is defined as the reappearance of the original infection following an initially false‐negative post‐eradication test result . A small amount of H pylori that has not been eradicated ( H pylori was hidden in the deep part of the stomach or the gastric epithelial metaplasia of the duodenum) or is in dormancy (eg H pylori coccoid forms) is recolonized, reproduced and eventually detected.…”

Section: Definition and Diagnosis Of H Pylori Recrudescencementioning

confidence: 99%

“…It can cause lifelong infection without eradication. Many studies showed that H pylori led to some important gastrointestinal diseases, such as chronic gastritis, peptic ulcer, gastric adenocarcinoma and mucosa‐associated lymphoid tissue lymphoma, and was associated with a variety of parenteral diseases such as idiopathic thrombocytopenic purpura. H pylori eradication significantly alleviated stomach inflammation, promoted ulcer healing and prevented gastric cancer .…”

Section: Introductionmentioning

confidence: 99%

“…H pylori eradication significantly alleviated stomach inflammation, promoted ulcer healing and prevented gastric cancer. 2 In 1994, H pylori was listed as Group I carcinogen. The 2015 Tokyo Global Consensus Report 4 defines H pylori gastritis as an infectious disease and recommends eradication therapy for H pylori-infected individuals, except in the case of competing considerations.…”

Section: Introductionmentioning

confidence: 99%

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Helicobacter pylori recrudescence and its influencing factors

Sun

Zhang

2019

J Cellular Molecular Medi

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Helicobacter pylori (H pylori) is known as one of the most common infectious pathogens, with high infection and recurrence rates worldwide. The prevalence of H pylori is up to 90% in developing countries, while the annual recurrence rate is much higher than that in developed countries. Recurrence can occur either by recrudescence or reinfection. Compared with reinfection, the time window for recrudescence is generally shorter, followed by the recurrence of H pylori–associated diseases in the short‐term. Many factors are involved in the H pylori reinfection, such as the prevalence of H pylori infection, living conditions and economic development, health conditions and so forth. Previous studies focused less on H pylori recrudescence. Therefore, the influencing factors for H pylori recrudescence needed further exploration. This study reviewed the recrudescence of H pylori infection and its influencing factors.

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Section: Influencing Factors Of H Pylori Recrudescencementioning

confidence: 96%

Section: Definition and Diagnosis Of H Pylori Recrudescencementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Helicobacter pylori recrudescence and its influencing factors

Sun

Zhang

2019

J Cellular Molecular Medi

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“…As the authors point out, such examples make clear that other factors, such as local customs, sanitation and crowding, likely influence recurrence rates. Additional factors which merit consideration include host factors such as genetics and immune function as well as organism factors such as antimicrobial resistance, urease activity and ability to assume the coccoid form . Furthermore, particularly where there is confusion about recrudescence vs reinfection, the choice of eradication therapy is likely to be important.…”

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confidence: 90%

Editorial: recurrence of Helicobacter pylori infection—still the same after all these years…

Shah

Chey

2017

Aliment Pharmacol Ther

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In the systematic review and meta-analysis by Hu et al, 3 the authors identified an overall mean annual recurrence rate of 4.3%(95% CI 4-5%). Not surprisingly, recurrence rates varied widely among countries from a high of 21.3% in Turkey to a low of 0.2% in the Netherlands. For its part, the recurrence rate for the USA was estimated to be 1%. In subgroup analyses, the authors found that low Human Development Index (HDI) and high population prevalence of H. pylori tended to predict a higher H. pylori recurrence rate.It is interesting that there were countries which broke with these

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