2011
DOI: 10.1111/j.1440-0960.2011.00745.x
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Role of genetics and sex steroid hormones in male androgenetic alopecia and female pattern hair loss: An update of what we now know

Abstract: The role of genetic predisposition and the influence of sex steroid hormones are indisputable to the pathogenesis of male androgenetic alopecia (MAGA). The role of sex steroid hormones in female pattern hair loss (FPHL) is less known. A good knowledge of the pathophysiology underlying MAGA and FPHL empowers the clinician to confidently counsel patients and make informed therapeutic decisions. Vigorous research in recent years has provided greater insight into the role of genetics and sex steroids in physiologi… Show more

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Cited by 108 publications
(96 citation statements)
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References 79 publications
(107 reference statements)
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“…Testosteronun DHT'ye dönüşümü genellikle tip II 5-α redüktaz tarafından gerçekleştirilir (2,9,12). DHT anagen fazda kısalma, telogen fazda uzama ve kıl foliküllerinde minyatürizasyon yapar (1).…”
Section: Etiyopatogenezunclassified
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“…Testosteronun DHT'ye dönüşümü genellikle tip II 5-α redüktaz tarafından gerçekleştirilir (2,9,12). DHT anagen fazda kısalma, telogen fazda uzama ve kıl foliküllerinde minyatürizasyon yapar (1).…”
Section: Etiyopatogenezunclassified
“…Bunun en önemli kanıtı kastre edilenlerde ve androjen duyarsızlığı sendromu ya da testiküler feminizasyon gibi androjen reseptör fonksiyon bozukluğu bulunanlarda kelliğin görülmemesidir (12). Güçlü androjenler arasında yer alan testosteron, saç …”
Section: Sınıflamaunclassified
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