Role of functionalized metal oxide–carbon nanocomposites in biomolecule detection

Younis, Sumaira; Zia, Rabisa; Taj, Ayesha; Rafiq, Amna; Hayat, Hunza; Nayab, Nafeesa; Khan, Waheed S.; Bajwa, Sadia Z.

doi:10.1016/b978-0-12-822694-0.00016-8

Cited by 1 publication

(1 citation statement)

References 119 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prepared complex showed a higher response as compared to bare Cu 2 O with a linear range of 16.65 mM of glucose concentration 34 . Similar process was reported in various literatures in which different combination of rGO with metal oxides have been studied to improve the sensing performance of non-enzymatic glucose sensor 17 , 35 – 38 . Although these composites have improved the sensitivity as compared to bare metal oxides, it still needs a lot of improvement in the linear range with high sensitivity to make it commercially viable.…”

Section: Introductionsupporting

confidence: 59%

Reduced graphene oxide supported MXene based metal oxide ternary composite electrodes for non-enzymatic glucose sensor applications

Gopal

Alzahrani

Assaifan

et al. 2022

Sci Rep

View full text Add to dashboard Cite

Diagnosis and monitoring of glucose level in human blood has become a prime necessity to avoid health risk and to cater this, a sensor’s performance with wide linearity range and high sensitivity is required. This work reports the use of ternary composite viz. MG–Cu2O (rGO supported MXene sheet with Cu2O) for non-enzymatic sensing of glucose. It has been prepared by co-precipitation method and characterized with X-ray powder diffraction, Ultraviolet–visible absorption spectroscopy (UV–Vis), Raman spectroscopy, Field emission scanning electron microscopy, High resolution transmission electron microscopy and Selected area diffraction. These analyses show a cubic structure with spherical shaped Cu2O grown on the MG sheet. Further, the electrocatalytic activity was carried out with MG–Cu2O sensing element by cyclic voltammetry and chronoamperometry technique and compared with M–Cu2O (MXene with Cu2O) composite without graphene oxide. Of these, MG–Cu2O composite was having the high defect density with lower crystalline size of Cu2O, which might enhance the conductivity thereby increasing the electrocatalytic activity towards the oxidation of glucose as compared to M–Cu2O. The prepared MG–Cu2O composite shows a sensitivity of 126.6 µAmM−1 cm−2 with a wide linear range of 0.01to 30 mM, good selectivity, good stability over 30 days and shows a low Relative Standard Deviation (RSD) of 1.7% value towards the sensing of glucose level in human serum. Thus, the aforementioned finding indicates that the prepared sensing electrode is a well suitable candidate for the sensing of glucose level for real time applications.

show abstract