Role of Functional Magnetic Resonance Imaging in the Presurgical Mapping of Brain Tumors

Jalilianhasanpour, Rozita; Beheshtian, Elham; Ryan, Daniel; Luna, Licia P.; Agarwal, Shruti; Pillai, Jay J.; Sair, Haris I.; Gujar, Sachin K.

doi:10.1016/j.rcl.2021.02.001

Cited by 9 publications

(4 citation statements)

References 89 publications

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“… 1 , 2 This imaging approach, which does not require penetration of the body, is crucial for pinpointing important brain areas that are at risk of damage during surgery. 3 Recent research has emphasized the crucial importance of fMRI in improving the accuracy of cortical mapping, which helps in performing brain tumor removal surgery while safeguarding vital neurological processes. 4 , 5 Neurosurgical efforts focus on maximizing tumor removal while minimizing neurological impairments.…”

Section: Introductionmentioning

confidence: 99%

Systematic Review Between Resting-State fMRI and Task fMRI in Planning for Brain Tumour Surgery

Abu Mhanna,

Omar,

Md Radzi

et al. 2024

JMDH

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As an alternative to task-based functional magnetic resonance imaging (T-fMRI), resting-state functional magnetic resonance imaging (Rs-fMRI) is suggested for preoperative mapping of patients with brain tumours, with an emphasis on treatment guidance and neurodegeneration prediction. A systematic review was conducted of 18 recent studies involving 1035 patients with brain tumours and Rs-fMRI protocols. This was accomplished by searching the electronic databases PubMed, Scopus, and Web of Science. For clinical benefit, we compared Rs-fMRI to standard T-fMRI and intraoperative direct cortical stimulation (DCS). The results of Rs-fMRI and T-fMRI were compared and their correlation with intraoperative DCS results was examined through a systematic review. Our exhaustive investigation demonstrated that Rs-fMRI is a dependable and sensitive preoperative mapping technique that detects neural networks in the brain with precision and identifies crucial functional regions in agreement with intraoperative DCS. Rs-fMRI comes in handy, especially in situations where T-fMRI proves to be difficult because of patient-specific factors. Additionally, our exhaustive investigation demonstrated that Rs-fMRI is a valuable tool in the preoperative screening and evaluation of brain tumours. Furthermore, its capability to assess brain function, forecast surgical results, and enhance decision-making may render it applicable in the clinical management of brain tumours.

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Section: Introductionmentioning

confidence: 99%

Systematic Review Between Resting-State fMRI and Task fMRI in Planning for Brain Tumour Surgery

Abu Mhanna,

Omar,

Md Radzi

et al. 2024

JMDH

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“…fMRI is a noninvasive technique that provides both the localization and lateralization of the language eloquent cortex. The technical aspects of presurgical fMRI have been discussed elsewhere (for review see Jalilianhasanpour et al, 2021) [9]. This method can be reliably used for language center identification, which can determine a patient's language laterality as well as estimate the functional risk and inform awake craniotomy language mapping, by determining the distance of the lesion from the eloquent cortex.…”

Section: Introductionmentioning

confidence: 99%

Beyond Broca’s and Wernicke’s: Functional Mapping of Ancillary Language Centers Prior to Brain Tumor Surgery

2023

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Functional MRI is a well-established tool used for pre-surgical planning to help the neurosurgeon have a roadmap of critical functional areas that should be avoided, if possible, during surgery to minimize morbidity for patients with brain tumors (though this also has applications for surgical resection of epileptogenic tissue and vascular lesions). This article reviews the locations of secondary language centers within the brain along with imaging findings to help improve our confidence in our knowledge on language lateralization. Brief overviews of these language centers and their contributions to the language networks will be discussed. These language centers include primary language centers of “Broca’s Area” and “Wernicke’s Area”. However, there are multiple secondary language centers such as the dorsal lateral prefrontal cortex (DLPFC), frontal eye fields, pre- supplemental motor area (pre-SMA), Basal Temporal Language Area (BTLA), along with other areas of activation. Knowing these foci helps to increase self-assurance when discussing the nature of laterality with the neurosurgeon. By knowing secondary language centers for language lateralization, via fMRI, one can feel confident on providing neurosurgeon colleagues with appropriate information on the laterality of language in preparation for surgery.

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“…Measuring the neural substrates associated with a motor or cognitive task using functional MRI (fMRI) has been extensively used in neurosciences in the past two decades (Sadraee et al, 2021) and has increasingly been utilized in clinical applications, for example, for preoperative mapping for brain surgery (Jalilianhasanpour et al, 2021; Manan et al, 2021) or neurofeedback therapies (Dudek & Dodell‐Feder, 2021; Thibault et al, 2018). The majority of studies evaluating task‐based brain activation do so by contrasting the blood oxygenation level‐dependent (BOLD) signals during active and control conditions as described by Ogawa et al (1990).…”

Section: Introductionmentioning

confidence: 99%

Test–retest reliability of a finger‐tapping fMRI task in a healthy population

Wüthrich

Lefebvre

Nadesalingam

et al. 2022

Eur J of Neuroscience

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Measuring brain activity during functional MRI (fMRI) tasks is one of the main tools to identify brain biomarkers of disease or neural substrates associated with specific symptoms. However, identifying correct biomarkers relies on reliable measures. Recently, poor reliability was reported for task-based fMRI measures. The present study aimed to demonstrate the reliability of a finger-tapping fMRI task across two sessions in healthy participants. Thirtyone right-handed healthy participants aged 18-60 years took part in two MRI sessions 3 weeks apart during which we acquired finger-tapping task-fMRI.We examined the overlap of activations between sessions using Dice similarity coefficients, assessing their location and extent. Then, we compared amplitudes calculating intraclass correlation coefficients (ICCs) in three sets of regions of interest (ROIs) in the motor network: literature-based ROIs (10-mm-radius spheres centred on peaks of an activation likelihood estimation), anatomical ROIs (regions as defined in an atlas) and ROIs based on conjunction analyses (superthreshold voxels in both sessions). Finger tapping consistently activated expected regions, for example, left primary sensorimotor cortices, premotor area and right cerebellum. We found good-to-excellent overlap of activations for most contrasts (Dice coefficients: .54-.82). Across time, ICCs showed large variability in all ROI sets (.04-.91). However, ICCs in most ROIs indicated fair-to-good reliability (mean = .52). The least specific contrast consistently yielded the best reliability. Overall, the finger-tapping task showed good spatial overlap and fair reliability of amplitudes on group level.

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Role of Functional Magnetic Resonance Imaging in the Presurgical Mapping of Brain Tumors

Cited by 9 publications

References 89 publications

Systematic Review Between Resting-State fMRI and Task fMRI in Planning for Brain Tumour Surgery

Systematic Review Between Resting-State fMRI and Task fMRI in Planning for Brain Tumour Surgery

Beyond Broca’s and Wernicke’s: Functional Mapping of Ancillary Language Centers Prior to Brain Tumor Surgery

Test–retest reliability of a finger‐tapping fMRI task in a healthy population

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