Role of Fluid Milk in Attenuating Postprandial Hyperglycemia and Hypertriglyceridemia

Abstract

Postprandial plasma glucose and triglyceride concentrations are predictive of relative cardiovascular disease (CVD) risk, and the pathogenesis of both insulin resistance and atherosclerosis has been attributed to acute states of hyperglycemia and hypertriglyceridemia. Postprandial lipemia and hyperglycemia suppress vascular reactivity and induce endothelial dysfunction. Epidemiological studies suggest that chronically-high consumption of milk and milk products is associated with a reduced risk of type 2 diabetes, metabolic syndrome, and CVD. The addition of dairy products to meals high in carbohydrates and fat may lessen these risks through reductions in postprandial glucose and triglyceride responses. Purported mechanisms include dairy proteins and bioactive compounds, which may explain the inverse relationship between dairy consumption and cardiometabolic diseases. The current review evaluates the available literature describing the relationships between metabolic dysfunction, postprandial metabolism, and vascular dysfunction and discusses the potential role of milk and dairy products in attenuating these impairments.

Relationship between Dietary Habits and Control of Lipid Profiles in Patients with Dyslipidemia Using Pravastatin

“…The association was significant in healthy individuals as well as in hypertriglyceridemic patients. Potential mechanisms linking dairy product consumption to lower TG levels include bioactive compounds or proteins found in dairy products [21]. Although the exact component responsible for decreasing TG level is difficult to ascertain, dairy proteins are generally insulinotrophic and bind to insulin receptors on vascular and endothelial smooth muscle cells [21,22].…”

“…Potential mechanisms linking dairy product consumption to lower TG levels include bioactive compounds or proteins found in dairy products [21]. Although the exact component responsible for decreasing TG level is difficult to ascertain, dairy proteins are generally insulinotrophic and bind to insulin receptors on vascular and endothelial smooth muscle cells [21,22]. After binding, vasodilation occurs, thereby increasing blood flow and facilitates the clearance and storage of TG and glucose [21,23].…”

Postprandial Bioactivity of a Spread Cheese Enriched with Mountain Tea and Orange Peel Extract in Plasma Oxidative Stress Status, Serum Lipids and Glucose Levels: An Interventional Study in Healthy Adults

“…The amount of food consumed and its composition, the consumption duration, the carbohydrate content, the rate of glucose absorption and insulin resistance are important factors that affect the degree of postprandial glycemia. The concentration of glucose in plasma, 2 h after consuming a meal, is a key factor in predicting the risk of cardiovascular disease [4]. Postprandial lipemia, on the other hand, is affected by changes in plasma lipids composition and concentration.…”

Insulin index of food products, its role in type 2 diabetes mellitus in overweight patients

“…Согласно обзору, молочные продукты оказывают благоприятное действие или по крайне мере нейтральны при СД-2 и метаболическом синдроме [17]. Согласно другому обзору, молочные продукты снижают риск СД-2 и сердечнососудистых заболеваний [18]. По разным данным, уровень глюкозы натощак не менялся или снижался после приема молочных продуктов; отмечались также другие благоприятные метаболические эффекты молока [18].…”

“…Согласно другому обзору, молочные продукты снижают риск СД-2 и сердечнососудистых заболеваний [18]. По разным данным, уровень глюкозы натощак не менялся или снижался после приема молочных продуктов; отмечались также другие благоприятные метаболические эффекты молока [18].…”