Role of E-cadherin in Progression of Oral Squamous Cell Carcinoma: A Retrospective Immunohistochemical Study

Gupta, Awadhesh; Sharma, S.; Batra, Monisha; Abidullah, Mohammed; Bhuvinder, Swathi; Katragadda, Padmavathi

doi:10.5005/jp-journals-10024-2389

Cited by 7 publications

(1 citation statement)

References 16 publications

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“…Even if they are found they are seen in superficial branches. Aneurysms in lingual artery (LA) are, usually pseudoaneurysms which can be the result of neoplasms, trauma or surgery [2][3][4][5] . Very scarce cases of aneurysm of the lingual artery are mentioned in literature [6][7][8] .…”

Section: Introductionmentioning

confidence: 99%

Pseudoaneursym Of Lingual ArteryA Rare Case Report

Bhardwaj¹,

Chaudhary²,

Lall³

et al. 2023

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Section: Introductionmentioning

confidence: 99%

Pseudoaneursym Of Lingual ArteryA Rare Case Report

Bhardwaj¹,

Chaudhary²,

Lall³

et al. 2023

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Pseudoepitheliomatous Hyperplasia: Harbinger of Underlying Squamous Cell Carcinoma - Lessons Learnt

Krishnamoorthy

Sekar

Joseph³

et al. 2022

ann urol oncol

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Pseudoepitheliomatous hyperplasia (PEH) is a benign condition marked by reactive epithelial proliferation seen in response to various insults like trauma, infection, persistent inflammation and neoplasia. In this report, we discuss a case of a 35-year-old man who presented with a perineal swelling, later turned into a non-healing ulcer, first diagnosed as PEH. Still, after clinical suspicion, a deeper biopsy was conducted, confirming the diagnosis of squamous cell carcinoma and directing treatment appropriately. Non-healing perineal lesions are not uncommon. Most of the lesions turn out to be Squamous Cell Carcinoma. But, if the histopathological picture suggests Pseudoepitheliomatous Hyperplasia, it is vital to consider the limitations of the biopsy, and a solid clinicopathological correlation is required to look aggressively for underlying Squamous Cell Carcinoma. Due to the benign nature of PEH, most cases are treated via excision biopsy, while grafts or flaps are occasionally required to restore severe tissue defects. It is therefore crucial to rule out and distinguish this condition from other benign and malignant conditions, as the treatment and prognosis differ widely. It is of utmost importance to sample the base of the lesion, analyze multiple sections, and consider clinical data to ensure an accurate diagnosis.

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State of the Art in the Diagnosis and Assessment of Oral Malignant and Potentially Malignant Disorders: Present Insights and Future Outlook—An Overview

Menditti,

Santagata,

Guida

et al. 2024

Bioengineering

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Oral Potentially Malignant Disorder (OPMD) is a significant concern for clinicians due to the risk of malignant transformation. Oral Squamous Cell Carcinoma (OSCC) is a common type of cancer with a low survival rate, causing over 200,000 new cases globally each year. Despite advancements in diagnosis and treatment, the five-year survival rate for OSCC patients remains under 50%. Early diagnosis can greatly improve the chances of survival. Therefore, understanding the development and transformation of OSCC and developing new diagnostic methods is crucial. The field of oral medicine has been advanced by technological and molecular innovations, leading to the integration of new medical technologies into dental practice. This study aims to outline the potential role of non-invasive imaging techniques and molecular signatures for the early detection of Oral Malignant and Potentially Malignant Disorders.

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Role of E-cadherin in Progression of Oral Squamous Cell Carcinoma: A Retrospective Immunohistochemical Study

Cited by 7 publications

References 16 publications

Pseudoaneursym Of Lingual ArteryA Rare Case Report

Pseudoaneursym Of Lingual ArteryA Rare Case Report

Pseudoepitheliomatous Hyperplasia: Harbinger of Underlying Squamous Cell Carcinoma - Lessons Learnt

State of the Art in the Diagnosis and Assessment of Oral Malignant and Potentially Malignant Disorders: Present Insights and Future Outlook—An Overview

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