Role of dysregulated macrophage subpopulation ratios and functional changes in the development of coronary atherosclerosis
Yingjie Xiao,
Xin Huang,
Yijun Xia
et al.
Abstract:Coronary heart disease is one of the most significant risk factors affecting human health worldwide. Its pathogenesis is intricate, with atherosclerosis being widely regarded as the leading cause. Aberrant lipid metabolism in macrophages is recognized as one of the triggering factors in atherosclerosis development. To investigate the role of macrophages in the formation of coronary artery atherosclerosis, we utilized single‐cell data from wild‐type mice obtained from the aortic roots and ascending aortas after… Show more
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