“…Most secondary colorectal cancers develop within 3 years of the initial diagnosis, and, since a portion of them steadily develop for 5 years after detection of primary gastric cancer [4,6], screening FCS should be performed for at least 5 years after endoscopic removal of gastric lesions. Meanwhile, the prevalence of overall colorectal polyps and of colorectal adenocarcinomas seen in this study is higher than that observed by previous studies which dealt with the prevalence of colorectal neoplasms in patients with gastric cancer, and reported frequencies of 31.4 % -32.4 % for all polyps [24,25] and 0.7 % -1.5 % for adenocarcinomas [6 -99. This contradiction may be explained by the fact that male sex, more advanced age (≥ 62 years), and a diagnosis of early gastric cancer were found to be the greatest risk factors for synchronous or metachronous colorectal adenocarcinoma in previous studies [6,7,24].…”