Role of colonoscopic biopsy in distinguishing between Crohn's disease and intestinal tuberculosis

Kirsch, Richard; Pentecost, Michelle; Hall, Philip D.; Epstein, David; Watermeyer, Gillian; Friederich, Philip W.

doi:10.1136/jcp.2005.032383

Cited by 115 publications

(73 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The cause of maximum affected low socio-economic group are in general ignorance and illiteracy; furthermore, other causes are living in the crowded environment as well as in the low ventilated rooms; thus people of low socio-economic condition got infection by inhalation easily [12]. By taking unhygienic food and unboiled milk the patients with low socio-economic condition has got alimentary infection which causes intestinal tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

Clinico-Demographic Characteristics of Intestinal Tuberculosis in Pre-Operative Unsuspected Laparotomy as Incidental Findings in Bangladesh

Rahman¹,

Ali²,

Yusuf³

et al. 2017

JTR

View full text Add to dashboard Cite

Background: Clinical presentation of intestinal tuberculosis is varied. It is also essential to know the clinical and demographic characteristics of incidentally detected intestinal tuberculosis patient. Objective: The purpose of the present study was to find out the clinic-demographic characteristics of intestinal tuberculosis in clinically and preoperatively unsuspected laparotomies. Methodology: This cross-sectional study was carried out in the Department of Surgery at Dhaka Medical College Hospital, Dhaka from March 2002 to March 2004 for a period of two (2) years. All the patients underwent laparotomy presented without any suspicion of pulmonary or intestinal tuberculosis were included as study population. Patients who were without the history of cough, haemoptysis, antitubercular drug therapy were included. Per operative suspicion was raised due to enlarged lymph nodes in mesentery, omental masses, ileocaecal masses, suspicious growth in ileum, omental thickening, perforation suspected by tuberculosis. Biopsy was taken from suspicious lesions. Histopathology was confirmed the tubercular lesion. Results: A total number of 300 patients under laparotomy were recruited for this study of which 38 positive cases were found in the study with a percentage of 12.7%. Maximum affected age group was 21 to 30 years which was 16 (42%) cases. Male was predominant to female which was 28 (73.7%) cases and 10 (26.3%) cases respectively. Low socioeconomic people are affected more (76.3%). Most 140common presentation in positive cases was acute and sub-acute intestinal obstruction 20 (52.6%) followed by intestinal perforation (26.31%). Conclusion: In conclusion young age male patient is the most commonly affected intestinal tuberculosis which is frequently presented with sub-acute intestinal obstruction among the preoperatively unsuspected laparotomy patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinico-Demographic Characteristics of Intestinal Tuberculosis in Pre-Operative Unsuspected Laparotomy as Incidental Findings in Bangladesh

Rahman¹,

Ali²,

Yusuf³

et al. 2017

JTR

View full text Add to dashboard Cite

show abstract

“…Parameter tersebut meliputi karakteristik granuloma seperti ukuran, jumlah, konfluens, nekrosis perkijuan, lokasi, mikrogranuloma, bentuk ulserasi dan kerusakan submukosa. 18,26 Gambaran histologis TB intestinal yang khas adalah konfluen, granuloma caseosa yang mengandung basil tahan asam dan dikelilingi limfoid cuff. Hal tersebut ditemukan pada semua lapisan dinding usus dan kelenjar getah bening regional.…”

Section: Histologiunclassified

“…18 Gambaran histopatologis TB intestinal dapat dilihat pada Gambar 2. 26 Gambaran histopatologis tersebut dapat membedakan TB intestinal dan penyakit Crohn. Namun, pada 52,7% kasus TB intestinal dan hampir semua kasus penyakit Crohn memberikan gambaran yang membingungkan.…”

Section: Histologiunclassified

Pendekatan Diagnosis dan Tatalaksana Tuberkulosis Intestinal

Murwaningrum¹,

Abdullah²,

Makmun³

2017

JPDI

View full text Add to dashboard Cite

ABSTRAKTuberkulosis (TB) telah menjadi masalah global yang terus membesar seiring dengan bertambahnya jumlah pasien TB. Infeksi TB masih merupakan hal yang umum ditemukan dan merupakan faktor penting terhadap angka kesakitan dan kematian, terutama pada negara yang belum dan sedang berkembang. Kasus Tuberkulosis usus (TB usus) juga meningkat seiring dengan meningkatnya jumlah kasus TB secara umum. Indonesia merupakan Negara ke-2 dengan prevalensi Tuberkulosis TB tertinggi di Asia Tenggara setelah Timor Leste pada tahun 2014. TB usus adalah manifestasi TB ekstrapulmonal terbanyak keenam.Manifestasi klinis yang tidak spesifik dan kadang menyerupai beberapa kondisi lain termasuk keganasan menyebabkan diagnosis TB usus sulit ditegakkan secara akurat. Temuan dari hasil endoskopi dan gambaran radiologi dari berbagai stage penyakit sudah sangat banyak, namun diagnosis tetap sulit dilakukan. Sampai saat ini belum ada metode tunggal yang dapat mendeteksi TB usus secara tepat dan akurat, berbagai metode investigasi telah digunakan dalam diagnosis TB usus. Diagnosis yang dilakukan sejak awal, pemberian terapi anti tuberculosis dan tindakan bedah adalah hal-hal esensial dalam pencegahan terjadinya kesakitan dan kematian akibat TB usus, sehingga dibutuhkan kombinasi penilaian klinis dan pemeriksaan berbagai modalitas. Pasien yang telah didiagnosis TB usus diberikan terapi obat anti tuberculosis (OAT) dan pertimbangan tindakan bedah jika mengalami komplikasi. Kata Kunci: diagnosis, tuberkulosis intestinal ABSTRACT Tuberculosis (TB) has become a resurgent global problem with increasing numbers of patients. TB infection is still common and remains an important cause of morbidity and mortality, particularly in underdeveloped and developing nations. Intestinal tuberculosis (intestinal TB) rates are rising, consistet with the overall trend. In 2014 Indonesia has the second highest TB prevalence in South East

show abstract

“…Moreover, clinical features and histological parameters in colonoscopic mucosal biopsy specimens may be of value in differentiating between the two diseases. 7 Over the years, use of the term indeterminate or intermediate colitis has broadened to include colonoscopic, radiographic, or histologic appearances that show an overlap of diagnostic criteria for UC and CD. Although ileocolonoscopic and histologic evaluation can differentiate between UC and CD in most cases, approximately 10% of patients have indeterminate colitis.…”

Section: Diagnosismentioning

confidence: 99%