2013
DOI: 10.1016/j.jad.2012.11.020
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Role of childhood adversity in the development of medical co-morbidities associated with bipolar disorder

Abstract: Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum. b s t r a c tObjective: A role for childhood adversity in the development of numerous medical conditions in adults has been d… Show more

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Cited by 65 publications
(59 citation statements)
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“…Childhood maltreatment, trauma and abuse have been found to play a role in developing migraine headache and converting episodic to daily migraine. 6,41,42 Neuroticism was strongly associated with migraine in both genders, and as neuroticism measures propensity to experience negative affect and stress, those with high neuroticism are less likely to be able to be adaptable and flexible in coping styles. 43–45 …”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Childhood maltreatment, trauma and abuse have been found to play a role in developing migraine headache and converting episodic to daily migraine. 6,41,42 Neuroticism was strongly associated with migraine in both genders, and as neuroticism measures propensity to experience negative affect and stress, those with high neuroticism are less likely to be able to be adaptable and flexible in coping styles. 43–45 …”
Section: Resultsmentioning
confidence: 99%
“…2 In addition, health care for BD costs more on a per capita basis than for depression, asthma, coronary artery disease, or diabetes, 3 and comorbid medical conditions negatively affect quality of life and contribute to the burden of illness. 4–6 Migraine is a common comorbidity of BD. In population-based studies, the rate of migraine in the general population is 9–15%, 7–12 whereas the rate of migraine co-morbidity with BD is 16–54%.…”
Section: Introductionmentioning
confidence: 99%
“…Eleven articles and 1 trial were screened for eligibility, of which 1 did not have a control group, [19] 1 did not focus on BD patients, [20] 2 were review articles, [21,22] and 1 was a case report. [23] The trial of NCT02657668 in the ClinicalTrials.gov was excluded because of lack of results of the study.…”
Section: Resultsmentioning
confidence: 99%
“…Maladaptive habits, including unhealthy diet and smoking, as well as environmental factors, including childhood abuse, have been consistently associated with pro-inflammatory activation 59 . For instance, individuals with a history of childhood abuse exhibit higher plasma CRP, IL-6 and TNF-α levels during adulthood in comparison to healthy controls 60 and are exposed to greater risk of chronic diseases in adulthood including cancer, depression, cardiovascular disease and metabolic syndrome 61 .…”
Section: Inflammatory Aberrations Associated With Depressionmentioning
confidence: 99%