Role of centralization of surgery in stage IB carcinoma of the cervix: A review of 498 cases

This study includes 278 cases of stage I and II cervical cancer subjected to radical hysterectomy and lymphadenectomy. The clinical experience of 278 cases is reviewed. Of these cases, 215 were in stage I, and 63 were in stage II. Intraoperative complications occurred at a rate of 9.7% and involved injuries to the great vessels, lower urinary tract, nerves, and rectum. Operative mortality was found to be 0.3%. Postoperative complications were observed in 20.1% of patients. Fistulae were observed in 8 (2.8%) patients. The overall survival rate was 83.8%. The 5-year survival rates for stages IA, IB, IIA, and IIB were 100.0%, 87.9%, 71.0%, and 64.0%, respectively. Pelvic lymph node metastases varied from 0% for stage IA to 40.0% for stage IIB and paraaortic involvement varied from 0% for stage IA to 50.0% for stage IIB. Radical surgery seems to be the treatment of choice for patients with early invasive cervical cancer.

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“…Yet much of the morbidity was minor and of brief duration (Tables IV and V). Mortality was also quite low as compared with recent series [4,6,8].…”

Section: Discussionmentioning

confidence: 60%

Radical hysterectomy with lymphadenectomy for treatment of early stage cervical cancer: Clinical experience of 278 cases

Ayhan

Tuncer

1991

Journal of Surgical Oncology

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“…Prognosis in early-stage cervical cancer is dependent on the presence of disease in the lymphatics. 4 It was therefore not surprising to find that in early disease with LVSI, most centers advocated assessment of the pelvic lymph nodes albeit without universal agreement as to the areas that should be included (with or without para-aortic nodes) and the acceptable nodal count.…”

Section: Nodal Assessmentmentioning

confidence: 99%

“…This reflects the possible unease at not assessing the lymphatics in a disease in which we know the presence of malignancy within this area is a poor prognostic factor. 4 As the stage increased, the number of departments offering initial lymphadenectomy before surgical excision of the tumor increased. The rationale is to exclude metastatic spread to the lymphatics, which would make fertility-conserving surgery inadvisable and chemoradiotherapy more appropriate.…”

Section: When Fertility Conservation Is Not Desiredmentioning

confidence: 99%

Survey on the Management of Early Cervical Cancer Among Members of the GCIG

Lindsay

Paul

Siddiqui

et al. 2012

International Journal of Gynecological Cancer

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“…Im Allgemeinen wird beim Zervixkarzinom die Durchführung einer systematischen Lymphonodektomie gefordert [17]. Bereits Monaghan konnte nachweisen, dass bei einer systematischen Lymphonodektomie ein Überlebensvorteil für die Patientinnen gegenüber dem alleinigen Sampling besteht [18]. Hacker beschrieb in seiner eigenen Analyse, dass Patientinnen auch von einer Entfernung von sog.…”

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