We investigate the ability of the nano‐scale III‐V MOSFETs with InGaAs, GaAs or InP channels by using the quantum‐corrected Monte Carlo (MC) simulation. The InGaAs channel shows the largest average electron velocity at the bottleneck, vs, because of the smallest electron effective mass, m * in the Γ valley. However, it is degraded by the electron rebound from the drain through the accumulation in the L valleys, when the gate voltage, Vgs, is highly biased. The electron rebound is more pronounced in the GaAs channel, because of the narrow Γ ‐ L valley separation. Meanwhile, the InP channel shows the smallest vs because of the largest m * in the Γ valley. However, the electron rebound is less pronounced, because of the smaller accumulation in the L valleys. On the other hand, the electron density at the potential bottleneck, nb, is largest in the InP channel, because of the largest gate capacitance owing to the highest density of states, DOS. Eventually, the InP channel shows the largest drain current, Ids (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)