Role of calcium phosphate and bioactive glass coating on in vivo bone healing of new Mg–Zn–Ca implant

Mahato, Arnab; De, Munmun; Bhattacharjee, Promita; Kumar, Vinod; Mukherjee, Prasenjit; Singh, Gajendra; Kundu, Biswanath; Balla, Vamsi Krishna; Nandi, Samit Kumar

doi:10.1007/s10856-021-06510-0

Cited by 17 publications

(14 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The peaks were observed at 25.85°, 28.92°, 31.84°, 32.18°, 34.1°, 41.5°and 50.3° of 2θ and corresponded to the planes (0 0 2), (2 1 0), (2 1 1), (1 1 2), (3 0 0), (3 1 1), and (2 1 3) respectively, which are well matched with standard JCPDS No. (09-0432) data of apatite. , Further, the high intense peak of apatite was observed in PCL/BG/GO and PCL/BG/ZnO. The results of elemental analysis using EDAX also reveals that the PCL/BG/ZnO and PCL/BG/GO systems show higher calcium phosphate deposition compared with other composite scaffolds.…”

Section: Resultsmentioning

confidence: 82%

See 1 more Smart Citation

Enhancing Bioactivity of Nanofibrous Poly(Caprolactone)/45S5 Bioglass Composite Scaffolds by Incorporation of Ag, GO, and ZnO Nanoparticles

Ramar,

Bensingh,

Bhuvana

2023

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

The present study endeavors toward the investigation on the bioactivity of nanofibrous scaffolds manufactured by the electrospinning process. Nanofibrous composite scaffolds of PCL with 45S5 bioactive glass and metal oxide nanoparticles were developed and characterized. The effects of incorporating silver (Ag), graphene oxide (GO), and zinc oxide (ZnO) nanoparticles into PCL/bioglass nanofibrous scaffolds on its geometry and physiochemical, morphological, mechanical, and biological properties were studied. The incorporation of GO and ZnO alters the fiber diameter, suggesting the methodology for controlling the porosity of the scaffolds. The results of FTIR and XRD confirm the structure of bioglass, Ag, GO and ZnO nanoparticles. The in vitro degradation studies in SBF solution provide evidence for the enhancement in the rate of apatite formation by the inclusion of nanoparticles as compared with PCL/BG scaffolds. The assessment of mechanical properties suggests the tensile strength was increased from 1.61 to 5 MPa in PCL/BG/ZnO system when compared with pristine PCL. The cell viability is also observed to be improved from 72% to 91% and 104% for PCL/BG/GO and PCL/BG/ZnO, respectively. The hemolytic activity studies confirm that all scaffolds are nonhemolytic in nature and PCL/BG/ZnO exhibits the least hemolytic activity of 0.65% among the other composite scaffolds, suggesting the better blood compatibility. The present study evidently shows the fact that incorporation of GO and ZnO nanoparticles with PCL in addition to BG accelerates the bioactivity and improves the mechanical strength of the scaffold.

show abstract

Section: Resultsmentioning

confidence: 82%

“…(09-0432) data of apatite. 30,31 Further, the high intense peak of apatite was observed in PCL/BG/GO and PCL/BG/ZnO. The results of elemental analysis using EDAX also reveals that the PCL/BG/ ZnO and PCL/BG/GO systems show higher calcium phosphate deposition compared with other composite scaffolds.…”

Section: Surface Morphological Analysismentioning

confidence: 82%

Enhancing Bioactivity of Nanofibrous Poly(Caprolactone)/45S5 Bioglass Composite Scaffolds by Incorporation of Ag, GO, and ZnO Nanoparticles

Ramar,

Bensingh,

Bhuvana

2023

ACS Biomater. Sci. Eng.

View full text Add to dashboard Cite

show abstract

“…Mahato et al [ 156 ] compared a magnesium-based metallic implant (Mg-Zn-Ca) (BM) with and without HAp (BMH) and bioactive glass S53P4 (BMG) coatings. Figure 10 shows the radiograph of the samples in a femoral bone defect in mice.…”

Section: Radiopacifiers In Glasses and Glass-ceramicsmentioning

confidence: 99%

“… Radiographs of BM ( a – c ), BMH ( d – f ) and BMG ( g – i ) placed in bone immediately after implantation (day 0) and 1 month and 2 months after surgery [ 156 ]. …”

Section: Figurementioning

confidence: 99%

Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics

et al. 2022

View full text Add to dashboard Cite

Radiopacity is sometimes an essential characteristic of biomaterials that can help clinicians perform follow-ups during pre- and post-interventional radiological imaging. Due to their chemical composition and structure, most bioceramics are inherently radiopaque but can still be doped/mixed with radiopacifiers to increase their visualization during or after medical procedures. The radiopacifiers are frequently heavy elements of the periodic table, such as Bi, Zr, Sr, Ba, Ta, Zn, Y, etc., or their relevant compounds that can confer enhanced radiopacity. Radiopaque bioceramics are also intriguing additives for biopolymers and hybrids, which are extensively researched and developed nowadays for various biomedical setups. The present work aims to provide an overview of radiopaque bioceramics, specifically crystalline, non-crystalline (glassy), and nanostructured bioceramics designed for applications in orthopedics, dentistry, and cancer therapy. Furthermore, the modification of the chemical, physical, and biological properties of parent ceramics/biopolymers due to the addition of radiopacifiers is critically discussed. We also point out future research lacunas in this exciting field that bioceramists can explore further.

show abstract

“…As a result, HA made from green mussel shell wastes has the potential feedstock as an implanted metal covering for AISI 316L. Despite having parallels to human teeth and bones [5][6][7], the HA exhibits remarkable biocompatibility, bioactivity, and osteoconductivity [8][9]. The widespread use of HA powder feedstock in medicine for bone scaffolds, medication delivery, and coating of metallic implants is due to its advantageous features [10].…”

Section: Introductionmentioning

confidence: 99%

Use of hydroxyapatite powder derived from green mussel shell wastes for coating on AISI 316L

Amin,

Ismail,

Jamari

et al. 2023

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

This study aimed to determine the effect of preheating AISI 316L metal substrate on the adhesion strength of the hydroxyapatite (HA) layer derived from green mussel shell waste deposit by the flame spray method. The deposition experiment was carried out in a spray gun with a distance of 10 mm with preheat of 200°C, 400°C, and 600°C. A sample without preheating was also a comparison. An optical microscope was for assessing the thickness and uniformity of the HA surface layer. The adhesion strength of the coatings followed the ASTM D4541 Standard. As a result, the adhesion strength of the HA coating increases with increasing preheat temperature. However, using Image-J software, at an initial heating temperature of 600 °C, the adhesion strength of the coating changed from adhesion- to adhesion-cohesive strength, leading to an increase in coating strength noted. The result can add knowledge to understanding the flame spray method for the HA-coated from green mussel shell waste on AISI 316L. The results obtained can increase knowledge to understand the method of flame spraying on HA-coated green mussel shell waste on AISI 316L. Preheat temperature, spray gun shooting distance, HA powder release, oxygen gas pressure, and LPG gas pressure can be used as references.

show abstract

Role of calcium phosphate and bioactive glass coating on in vivo bone healing of new Mg–Zn–Ca implant

Cited by 17 publications

References 55 publications

Enhancing Bioactivity of Nanofibrous Poly(Caprolactone)/45S5 Bioglass Composite Scaffolds by Incorporation of Ag, GO, and ZnO Nanoparticles

Enhancing Bioactivity of Nanofibrous Poly(Caprolactone)/45S5 Bioglass Composite Scaffolds by Incorporation of Ag, GO, and ZnO Nanoparticles

Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics

Use of hydroxyapatite powder derived from green mussel shell wastes for coating on AISI 316L

Contact Info

Product

Resources

About