Role of bioactive metabolites from Acremonium camptosporum associated with the marine sponge Aplysina fulva

Martins, Thamires; Schinke, Cláudia; Queiroz, S. C. do N. de; Braga, Patrícia Aparecida de Campos; Silva, Fábio S.P.; Melo, I. S. de; Reyes, Felix G. R.

doi:10.1016/j.chemosphere.2021.129753

Cited by 6 publications

(5 citation statements)

References 63 publications

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“…Among them, one strain produced 10 secondary metabolites and some of them exhibited antimicrobial and antiviral activities, and antifouling ( Bovio et al, 2019a , b ). One Ascomycota strain isolated from mid-Atlantic San Peter and San Paul Archipelago A. fulva produced secondary metabolites with antibacterial activities ( Martins et al, 2021 ). It is tempting to speculate that Ascomycota members might be responsible for the defense of the host sponges.…”

Section: Discussionmentioning

confidence: 99%

Prokaryotic, Fungal, and Unicellular Eukaryotic Core Communities Across Three Sympatric Marine Sponges From the Southwestern Atlantic Coast Are Dominated Largely by Deterministic Assemblage Processes

et al. 2021

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Marine sponges are known to harbor a diverse and complex microbiota; however, a vast majority of surveys have been investigating the prokaryotic communities in the north hemisphere and Australia. In addition, the mechanisms of microbial community assembly are poorly understood in this pivotal player of the ecosystem. Thus, this survey addressed the holobiome of the sponge species in the São Paulo region (Brazil) for the first time and investigated the contribution of neutral and niche processes of prokaryotic, fungal, and unicellular eukaryotic assemblage in three sympatric species Aplysina caissara, Aplysina fulva, and Tedania ignis along with environmental samples. The compositions of the holobiome associated with the sponges and detected in environmental samples were strikingly different. Remarkably, between 47 and 88% of the assigned operational taxonomic units (OTUs) were specifically associated with sponge species. Moreover, around 77, 69, and 53% of the unclassified OTUs from prokaryotic, fungal, and unicellular eukaryotic communities, respectively, showed less than 97% similarity with well-known databases, suggesting that sponges from the southwestern Atlantic coast are an important source of microbial novelty. These values are even higher, around 80 and 61% of the unclassified OTUs, when excluding low abundance samples from fungal and unicellular eukaryotic datasets, respectively. Host species were the major driver shaping the sponge-associated microbial community. Deterministic processes were primarily responsible for the assembly of microbial communities in all sponge species, while neutral processes of prokaryotic and fungal community assembly were also detected in the sympatric A. caissara and T. ignis replicates, respectively. Most of the species-rich sponge-associated lineages from this region are also found in the Northern seas and many of them might play essential roles in the symbioses, such as biosynthesis of secondary metabolites that exhibit antimicrobial and antiviral activities, as well as provide protection against host predation. Overall, in this study the microbiota was assembled by interactions with the host sponge in a deterministic-based manner; closely related sponge species shared a strong phylogenetic signal in their associated prokaryotic and fungal community traits and Brazilian sponges were a reservoir of novel microbial species.

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Section: Discussionmentioning

confidence: 99%

Prokaryotic, Fungal, and Unicellular Eukaryotic Core Communities Across Three Sympatric Marine Sponges From the Southwestern Atlantic Coast Are Dominated Largely by Deterministic Assemblage Processes

et al. 2021

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“…Previous studies indicate that compounds isolated have antibacterial activity (Yu-heng et al 2019). Acremonidin A-C compounds isolated from Acremonium camptosporum showed antibacterial activity (Martins et al 2021). The gancidin W compound found in the genus Acremonium has antibacterial (Khan et al 2021).…”

Section: Discussionmentioning

confidence: 99%

Diversity and antibacterial activity of endophytic fungi isolated from the medicinal plant of Syzygium jambos

et al. 2022

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Abstract. ‘Aini K, Elfita, Widjajanti H, Setiawan A. 2022. Diversity and antibacterial activity of endophytic fungi isolated from the medicinal plant of Syzygium jambos. Biodiversitas 23: 2981-2989. Currently, antimicrobial resistance is one of the most important threats to global public health. This is due to the various mechanisms of antimicrobial resistance. Thus, the need for new sources of bioactive compounds outside conventional antibiotics is a top priority. This investigation evaluated the diversity and antibacterial activities of endophytic fungi isolated from the leaves and root bark of jambu mawar (Syzygium jambos (L.) Alston). The endophytic fungi were grown on PDA media, and their antibacterial activities were tested using the Kirby-Bauer method on two Gram-positive and two Gram-negative bacteria. A total of 10 (SJD1-SJD10) and 11 isolates (SJA1-SJA11) of endophytic fungi were identified from the leaves and root bark of S. jambos, respectively. Among them, SJA8 isolate exhibited strong antibacterial activity. Based on morphological characterization and phylogenetic tree analysis, SJA8 was identified as Pleiocarpon livistonae. Isolation and identification of pure compounds from the fungi may reveal potential candidates for new antibiotic substances.

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“…By using UPLC-ESI-QToF/MS analysis, Martins et al identified acremonidins A ( 287 ), B ( 288 ), C ( 289 ), G ( 290 ) and acremoxanthones A ( 291 ), B ( 292 ), D ( 293 ), F ( 294 ), and G ( 295 ) ( Figure 27 ) from the EtOAc extracts of a culture broth and mycelia of Acremonium camptosporum , isolated from a marine sponge, Aplysina fulva , which was collected from the mid-Atlantic Saint Peter and Saint Paul Archipelago, Brazil [ 126 ].…”

Section: Anthraquinoid Polyketides and Their Analogues From Marine-de...mentioning

confidence: 99%

Anthraquinones and Their Analogues from Marine-Derived Fungi: Chemistry and Biological Activities

et al. 2022

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Anthraquinones are an interesting chemical class of polyketides since they not only exhibit a myriad of biological activities but also contribute to managing ecological roles. In this review article, we provide a current knowledge on the anthraquinoids reported from marine-derived fungi, isolated from various resources in both shallow waters such as mangrove plants and sediments of the mangrove habitat, coral reef, algae, sponges, and deep sea. This review also tentatively categorizes anthraquinone metabolites from the simplest to the most complicated scaffolds such as conjugated xanthone–anthraquinone derivatives and bianthraquinones, which have been isolated from marine-derived fungi, especially from the genera Apergillus, Penicillium, Eurotium, Altenaria, Fusarium, Stemphylium, Trichoderma, Acremonium, and other fungal strains. The present review, covering a range from 2000 to 2021, was elaborated through a comprehensive literature search using the following databases: ACS publications, Elsevier, Taylor and Francis, Wiley Online Library, MDPI, Springer, and Thieme. Thereupon, we have summarized and categorized 296 anthraquinones and their derivatives, some of which showed a variety of biological properties such as enzyme inhibition, antibacterial, antifungal, antiviral, antitubercular (against Mycobacterium tuberculosis), cytotoxic, anti-inflammatory, antifouling, and antioxidant activities. In addition, proposed biogenetic pathways of some anthraquinone derivatives are also discussed.

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Role of bioactive metabolites from Acremonium camptosporum associated with the marine sponge Aplysina fulva

Cited by 6 publications

References 63 publications

Prokaryotic, Fungal, and Unicellular Eukaryotic Core Communities Across Three Sympatric Marine Sponges From the Southwestern Atlantic Coast Are Dominated Largely by Deterministic Assemblage Processes

Prokaryotic, Fungal, and Unicellular Eukaryotic Core Communities Across Three Sympatric Marine Sponges From the Southwestern Atlantic Coast Are Dominated Largely by Deterministic Assemblage Processes

Diversity and antibacterial activity of endophytic fungi isolated from the medicinal plant of Syzygium jambos

Anthraquinones and Their Analogues from Marine-Derived Fungi: Chemistry and Biological Activities

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