2002
DOI: 10.1097/00006454-200201000-00006
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Role of Bartonella henselae in the etiology of Henoch-Schönlein purpura

Abstract: The results of this study indicate a significant association of antecedent B. henselae infection with HSP. The frequency of this association (67%) exceeds that of previously ascribed etiologic agents for this disease, such as the group A Streptococcus.

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Cited by 62 publications
(32 citation statements)
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“…Cases of osteomyelitis have also been described [148]. A causative role for B. henselae in Henoch-Schonlein purpura (HSP) was suggested based on serological evidence, as 12 (67%) of 18 HSP patients were seropositive versus only 8 (14%) of 57 controls [9]. HSP is an immune-mediated vasculitis that is characterized by excessive IgA production and frequently associated with thrombocytopenia.…”
Section: Humansmentioning
confidence: 99%
“…Cases of osteomyelitis have also been described [148]. A causative role for B. henselae in Henoch-Schonlein purpura (HSP) was suggested based on serological evidence, as 12 (67%) of 18 HSP patients were seropositive versus only 8 (14%) of 57 controls [9]. HSP is an immune-mediated vasculitis that is characterized by excessive IgA production and frequently associated with thrombocytopenia.…”
Section: Humansmentioning
confidence: 99%
“…81,87 Other rheumatic manifestations associated with Bartonella infection in humans include erythema nodosum, 81 leukocytoclastic vasculitis, 88 fever of unknown origin with myalgia, 84 and arthralgia. 81 A causative role for B henselae in Henoch-Schönlein purpura was recently suggested on the basis of serologic evidence; results of a study 89 indicated that 12 of 18 (67%) patients with Henoch-Schönlein purpura were seropositive against B henselae versus only 8 of 57 (14%) unaffected individuals. Henoch-Schönlein purpura is an immune-mediated vasculitis that is characterized by excessive IgA production.…”
Section: Clinical Featuresmentioning
confidence: 99%
“…Others found serological evidence for an association with infections with other bacteria such as Bartonella henselae or viruses such as parvovirus B19 and hepatitis C virus [146,147,148].…”
Section: Infectious and Non-infectious Agentsmentioning
confidence: 99%