Role of Bacterial Vaginosis in threatened preterm and preterm labour, and its screening

Jayakrishnan, Chithra; Rajalekshmi, M; Raghunath, Nithya; S, Vijay Narayanan

doi:10.5958/2394-2754.2016.00031.x

Cited by 2 publications

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“…Bacterial vaginosis is one of the most common causes that cause preterm labor. [6][7][8] Based on the above background, researchers are interested in conducting studies to assess differences in fetal fi bronectin levels, pH of vaginal secretions, and cervical length in preterm pregnant women with and without the threat of preterm labor.…”

Section: Introductionmentioning

confidence: 99%

Threatened Preterm Labor: Which are become Preterm Labor?

Yeni

Tambunan

Hasanuddin

2020

Indones J Obstet Gynecol

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Objective: The research was aimed to show about characteristics of subject, fetal fibronectin, vaginal pH, cervical length of women with threatened preterm labor, and which are become preterm labor? Preterm labor is occurs most often in 20 weeks gestation to less than 37 weeks gestation. This condition is concerned about Obstetric problem and associated with significant neonatal morbidity and mortality.Methods: This study used the design of case control where preterm pregnant women who become research subjects divided into two groups with threat and without the threat of pre-term labor. Fetal fibronectin , vaginal pHand cervical length than in both groups were evaluated as a risk factor for preterm labor. Mann-Whitney test , Wilcoxon test and Chi-squared test were used as statistical tests with a confidence level of 95%.Results: A total of 86 preterm pregnant women involved in this study with an average age 30 , 5 ± 6.25 (group threat) 32.16 ± 5.25 (non-threatening). Comparison of fetal fibronectin (p = 0.005), vaginal PH(p <0.001) and length of the cervix (p <0.001) between the two groups showed a significant difference. A total of 8 subjects of the 43 in the group of pregnant women with the threat pretem labor experiencing preterm labor .Conclusion: The size of a short cervical length, an increase in the pH of the vaginal secretions and increased levels of fetal fibronectin is a clinical indicator for screening during pregnancy to assess the risk of a preterm labor .Keywords: cervical length, fetal fibronectin, pretermlabor , vaginal pH of the secretions. Abstrak Tujuan: Persalinan preterm adalah persalinan yang terjadi padausia kehamilan 20 hingga kurang dari37 minggu. Kondisi inimerupakanpermasalahan yang sangat mengkhawatirkan dalam bidang kebidanan dan dikaitkan dengan morbiditas dan kematian neonatal yang signifikan. Evaluasi dan skrining terhadap berbagai faktor resiko terjadinya ancaman persalinan preterm adalah hal terpenting dalam mencegah berbagai komplikasi yang mungkin timbul.Metode: Penelitian ini menggunakan desain case control dimana wanita hamil preterm yang menjadi subjek penelitian terbagi menjadi dua yakni kelompok dengan ancaman dan tanpa ancaman persalinan preterm. Fetal fibronectin, pH sekret vagina dan panjang serviks dibandingkan diatara kedua kelompok sebagai faktor resiko ancaman persalinan preterm. Mann-Whitney test, Wilcoxon test dan Chi – squared digunakan sebagai uji statistik dengan tingkat kepercayaan 95%.Hasil: Sebanyak 86 wanita hamil preterm terlibat dalam penelitian ini dengan rerata usia 30,5 ± 6,25 (kelompok ancaman) 32,16 ± 5,25 (tanpa ancaman). Perbandingan Fetal fibronectin (p=0,005), pH sekret vagina (p<0,001) dan panjang serviks (p<0,001) antar kedua kelompok menunjukkan adanya perbedaan yang bermakna. Sebanyak 8 subjek dari 43 pada kelompok wanita hamil pretem dengan ancaman persalinan preterm yang mengalami persalinan pretermKesimpulan:Ukuran panjang serviks yang pendek, peningkatan pH sekret vagina dan peningkatan kadar fetal fibronectin merupakan indikator klinis untuk skrining selama kehamilan guna menilai resiko terjadinya persalinan pretermKata kunci: fetal fibronectin, persalinan preterm, Ph vagina, panjang cerviks

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Section: Introductionmentioning

confidence: 99%

Threatened Preterm Labor: Which are become Preterm Labor?

Yeni

Tambunan

Hasanuddin

2020

Indones J Obstet Gynecol

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“…It is a polymicrobial syndrome characterized by a shift of the vaginal flora from the dominant Lactobacillus species to acquisition of diverse Gram-negative and variable anaerobic and facultative bacteria (Fredricks et al, 2005;Livengood, 2009;Rubins, 2011). Bacterial vaginosis is strongly associated with serious pregnancy-related outcomes including chorioamnionitis, spontaneous abortion, preterm labor (DiVico et al, 2011;Das et al, 2011;Jayakrishnan et al, 2016), pelvic inflammatory disease (Taylor et al, 2013), postpartum and postabortal endometritis (Haggerty et al, 2004). Moreover, it has been found to be associated with increased susceptibility to sexually-transmitted infections, such as Neisseria gonorrhoeae, Trichomonas vaginalis, Chlamydia trachomatis, Candida spp., and even human immunodeficiency virus (Martin et al, 1999;Bhalla et al, 2007;Allsworth and Peipert, 2011).…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of Bacterial Vaginosis among Symptomatic Egyptian Women: Value of Assessing Bacterial Sialidase Activity

Hafez¹,

El-Metwally²

2017

Int.J.Curr.Microbiol.App.Sci

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Role of Bacterial Vaginosis in threatened preterm and preterm labour, and its screening

Cited by 2 publications

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Threatened Preterm Labor: Which are become Preterm Labor?

Threatened Preterm Labor: Which are become Preterm Labor?

Diagnosis of Bacterial Vaginosis among Symptomatic Egyptian Women: Value of Assessing Bacterial Sialidase Activity

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