Role of autopsy in diagnosing asplenia and right bilobed lung in a fetus with dextrocardia

Abstract

We present a unique case of a fetus with dextrocardia, asplenia and a right bilobed lung in a primigravida woman in her 20s at 21 weeks’ gestation. Prenatal ultrasound examination revealed dextrocardia and other anomalies such as atrioventricular septal defect and situs ambiguous with the gallbladder on the left, leading to termination of the pregnancy. Fetal autopsy confirmed the diagnosis, detected additional findings such as asplenia and right bilobed lung missed on ultrasound and highlighted the importance of autopsy in prenatal diagnosis. This rare case emphasises the value of a comprehensive prenatal assessment, fetal autopsy and a multidisciplinary approach in diagnosing, managing and counselling families affected by congenital anomalies. Timely detection and appropriate genetic counselling can guide affected families in making informed decisions regarding future pregnancies while providing closure and support in their grieving process.