Role of antimicrobial susceptibility testing on efficacy of triple therapy in Helicobacter pylori eradication

Toracchio, Sonia; Cellini, Luigina; Ferri, Alessandra; Malatesta, Maria Grazia; Cappello, G.; Ciccaglione, Antonio Francesco; Campli, Emanuela Di; Grossi, Laurino; Marzio, L.

doi:10.1016/s1590-8658(00)80534-4

Cited by 33 publications

(54 citation statements)

References 5 publications

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“…Many studies have highlighted the difficulties of retreatment, and it can be stated that the best available first-line treatment regimen is still the best rescue treatment (6). The H. pylori eradication rate was significantly improved when antibiotic therapy was performed on the basis of the results of antimicrobial susceptibility testing (18 and 17% improvement in our preliminary results and another report [17], respectively).…”

mentioning

confidence: 51%

Impact of Clarithromycin Resistance on Eradication of Helicobacter pylori in Infected Adults

Lee

Shin²,

Roe

et al. 2005

Antimicrob Agents Chemother

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The outcome of Helicobacter pylori infection was analyzed in 114 dyspeptic patients treated with triple-drug therapy including clarithromycin. Clarithromycin resistance (in 20.2% of our isolates) was mainly caused by an A2142G mutation in the 23S rRNA gene of H. pylori. H. pylori eradication was obtained in all patients with clarithromycin-susceptible isolates but not in any patients with clarithromycin-resistant isolates (P ‫؍‬ 0.0001). Therefore, it would be useful to conduct H. pylori antimicrobial susceptibility testing of the first gastric biopsy culture before choosing the first three drugs for therapy of infected patients.

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mentioning

confidence: 51%

Impact of Clarithromycin Resistance on Eradication of Helicobacter pylori in Infected Adults

Lee

Shin²,

Roe

et al. 2005

Antimicrob Agents Chemother

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“…Since resistance to antibiotics is the main reason for treatment failure, knowledge about minimal inhibitory concentration (MIC) values of the prescribing antibiotics for bacterial strains could help clinicians select the best choice of medication in each geographic region (7).…”

Section: Introductionmentioning

confidence: 99%

Resistance Rate and Minimum Inhibitory Concentration of Metronidazole Among Helicobacter pylori Strains in Tehran, Iran

Mahnaz

Alebouyeh

Farzi

et al. 2016

Arch Clin Infect Dis

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“…The optimal dosing of the selected drugs is based on the results of clinical trials. Improvement of this 'one therapy for all' strategy is possible if bacterial sensitivities are used to select the regimen (6)(7)(8). This is only possible after endoscopy, with culture of the biopsies obtained.…”

Section: Uringmentioning

confidence: 99%

Eradication Therapy Should Be Different for Dyspeptic Patients than for Ulcer Patients

Boer

2003

Canadian Journal of Gastroenterology and Hepatology

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Role of antimicrobial susceptibility testing on efficacy of triple therapy in Helicobacter pylori eradication

Cited by 33 publications

References 5 publications

Impact of Clarithromycin Resistance on Eradication of Helicobacter pylori in Infected Adults

Impact of Clarithromycin Resistance on Eradication of Helicobacter pylori in Infected Adults

Resistance Rate and Minimum Inhibitory Concentration of Metronidazole Among Helicobacter pylori Strains in Tehran, Iran

Eradication Therapy Should Be Different for Dyspeptic Patients than for Ulcer Patients

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