Role of antibiotics in post-tonsillectomy morbidities; A systematic review

Abdelhamid, Amr; Sobhy, Tamer S.; El-Mehairy, Hazem Mounir; Hamid, Osama

doi:10.1016/j.ijporl.2018.12.011

Cited by 15 publications

(7 citation statements)

References 16 publications

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“…The results are consistent with the 2019 meta-analysis by Abdelhamid et al [19]. In 2019, AAO [1] updated the guidelines for the application of antibiotics after tonsillectomy in children, and clearly pointed out that children with heart murmur, internal implants, previous history of chronic tonsillitis, tonsil tumors, tonsillectomy combined with other pharyngeal operations were indications of antibiotic use.…”

Section: Discussionsupporting

confidence: 84%

The Efficacy of Perioperative Antibiotic Therapy in Adenotonsillectomy Children

Wang,

Zhao,

Wang

et al. 2023

Preprint

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Purpose: This prospective study was to evaluate the role of perioperative antibiotics use in children after adenotonsillectomy. Methods: A total of 246 children undergoing adenotonsillectomy admitted to our department from September 6th 2021 to September 5th 2022 were collected and randomly divided into observation group (128 cases) and control group (118 cases). The observation group received ampicillin sulbactam sodium intravenously 30min before and the day after surgery, while the control group was given saline instead. SPSS 27.0 was used for statistical analysis. Two independent samples mean T-test was used to evaluate the throat pain scores consecutive 3 days after the surgery, the time to resume to normal diet and the wound healing time between the two groups. Logistic regression analysis was used to evaluate the independent risk factors of the two groups. The generalized estimation model was used to evaluate the correlation between age and postoperative pain scores and the relationship between the different tonsillar bed grading and postoperative pain scores. Results: The pain scores were 5.83±1.879, 5.20±1.933 and 4.02±1.936 in the observation group and 6.83±1.892, 6.17±2.001 and 5.29±2.068 in the control group on day 1 to 3 after surgery, respectively. The difference between the two groups was statistically significant (P<0.01); The time of pain disappearance was (6.24±2.121) d in the observation group and (7.73±2.210) d in the control group, and the difference between the two groups was statistically significant (P<0.01). The wound repair time was (18.66±2.200) d in the observation group and (18.70±2.468) d in the control group. There was no significant difference between the two groups (P =0.874). Logistic regression analysis showed that fever was an independent risk factor for the two groups and was negatively correlated (B=-1.237, P<0.001, OR=0.290); Generalized estimation model showed that there was a positive correlation between age and pain scores (P<0.001) and with the increasing grading of tonsillar bed, the higher the pain scores was (P<0.001). Conclusions: Perioperative use of antibiotics in children with adenotonsillectomy can effectively reduce postoperative fever, throat pain symptoms and shorten the pain time. With the increasing of tonsillar bed grading, perioperative antibiotic therapy was more necessary.

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Section: Discussionsupporting

confidence: 84%

The Efficacy of Perioperative Antibiotic Therapy in Adenotonsillectomy Children

Wang,

Zhao,

Wang

et al. 2023

Preprint

View full text Add to dashboard Cite

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“…Indeed, in the authors' previous study, a combined "hot" and "cold" dissection technique led to a reduced haemorrhage rate. 7 In terms of other risk factors, trialled interventions (eg antibiotics, steroids, tranexamic acid and NSAIDs) have demonstrated minimal or no relationship with risk of post-tonsillectomy haemorrhage, [18][19][20][21] the ratio of trainees to consultants operating is unlikely to have changed over the study period, and the improved haemorrhage rates with the introduction of tonsillotomy would have led to a reduction in complications depending on the adoption levels in Scotland. 22 addition, whilst there has been an increase in the provision of day-case tonsillectomies over recent years, 23 this has been demonstrated to be safe practice, 24 and disparities in day-case tonsillectomy rates within our study has not resulted in a demonstrable difference in tonsillectomy outcomes (eg NHS Greater Glasgow & Clyde provides predominantly day-case procedures, whilst NHS Lothian provides predominantly inpatient tonsillectomies in adults).…”

Section: Improved Education Of Patients General Practitioners and Acc...mentioning

confidence: 99%

Pan‐Scotland tonsillectomy outcomes: A national cross‐sectional study

Milner

Hilmi

Marshall

et al. 2020

Clinical Otolaryngology

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Post-tonsillectomy haemorrhage is the principal complication that can occur following tonsillectomy. The consequences for the patient can include hospital admission, blood transfusion, return to theatre for arrest of haemorrhage and rarely mortality. 1 It is therefore of vital importance to accurately determine the rate of post-tonsillectomy haemorrhage and to identify factors that would decrease its incidence. The National Prospective Tonsillectomy Audit (NPTA), published in 2005, was conducted with the aim of addressing these issues. 2 It

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“…36,37 In regard with the use of antibiotic, our findings were in consistent with a recent, meta-analysis which showed that, the use of antibiotic did not reduce the incidence posttonsillectomy bleeding. 38 Moreover, the use of antibiotics in tonsillectomy patients does not comply with the recommended protocols of antibiotics usage. 39 Local anesthesia was also found to be a statistically nonsignificant risk factor for post-tonsillectomy bleeding.…”

Section: Figure1mentioning

confidence: 99%

Evaluation of Secondary Post-Tonsillectomy Bleeding among Children in Saudi Arabia: Risk Factor Analysis

et al. 2020

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Background: Tonsillectomy is one of the most widely recognized surgeries for tonsillitis. It is the default surgery option for obstructive sleep apnea, recurrent tonsillitis, and recurrent peritonsillar abscess. However, there are limited risk factor analyses in Saudi Arabia related to tonsillectomy. The goal of study is to evaluate and analyze the risk factors for secondary post-tonsillectomy bleeding in Saudi Arabia. Method: This retrospective review study was directed at King Abdullah Specialized Children’s Hospital, Riyadh, Saudi Arabia. Univariate and multivariate investigations were performed to decide the risk factors. Results: A total of 713 children were included. Post-tonsillectomy bleeding occurred in only 5.3% of tonsillectomies. There was no seasonal variation impact on post-tonsillectomy bleeding rate ( P = .8). The multivariate analysis showed a significant association between post-tonsillectomy bleeding and both age (odds ratio [OR] = 1.156; 95% CI: 1.007-1.326; P = .039) and sleep disorder breathing/obstructive sleep apnea (OR = 3.581; 95% CI: 1.454-8.820; P = .006). Conclusion: This study revealed that age, sleep disorder/obstructive sleep apnea, and longer hospital stay after tonsillectomy are significant risk factors for post-tonsillectomy bleeding. This study provides an important baseline for further local studies in the future.

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Role of antibiotics in post-tonsillectomy morbidities; A systematic review

Cited by 15 publications

References 16 publications

The Efficacy of Perioperative Antibiotic Therapy in Adenotonsillectomy Children

The Efficacy of Perioperative Antibiotic Therapy in Adenotonsillectomy Children

Pan‐Scotland tonsillectomy outcomes: A national cross‐sectional study

Evaluation of Secondary Post-Tonsillectomy Bleeding among Children in Saudi Arabia: Risk Factor Analysis

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