Role of and spores in the pathogenesis of asthma

Licorish, Kenrick; Novey, Harold S.; Kozak, Peter P.; Fairshter, Ronald D.; Wilson, Archie F.

doi:10.1016/0091-6749(85)90755-9

Cited by 181 publications

(85 citation statements)

References 21 publications

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“…Indirect evidence of allergic IgE-mediated responses to fungi was provided by Licorish et al (27) who performed bronchial challenges on seven young adults with mild asthma using either Alternaria or Penicillium spores, depending upon the patient's allergy (approximately 2,000 and 10,000 spores/mi3, respectively). Pulmonary function tests and clinical symptoms were consistent with both immediate and late onset asthmatic responses.…”

Section: Resultsmentioning

confidence: 99%

The Effect of Outdoor Fungal Spore Concentrations on Daily Asthma Severity

Delfino¹,

Zeiger²,

Seltzer³

et al. 1997

Environmental Health Perspectives

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The relationship between day-to-dy changes The present study was designed to investigate the potential interactive and independent effects of ozone (03) and outdoor aeroallergens (pollens and molds) on daily asthma severity. This was carried out using the panel study design, which is characterized by longitudinal analyses of daily data for a panel of asthmatics, with each subject acting as his or her own control. This study was conducted in the small Southern California community of Alpine, California, over an 8-week period from 9 May through 3 July 1994. The time period was selected to maximize both 03 and fungal spore exposures, and followed the peak spring pollen season for the area. This study represents

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Section: Resultsmentioning

confidence: 99%

The Effect of Outdoor Fungal Spore Concentrations on Daily Asthma Severity

Delfino¹,

Zeiger²,

Seltzer³

et al. 1997

Environmental Health Perspectives

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“…Indoor dampness, water damage, and fungi have been associated with respiratory complaints (Martin 1987;Andrae 1988;Brunekreef 1989;Dales 1991;Dales 1991b;Brunekreef 1992;Summerbell 1992;Jaakkola 1993;Joki 1993;Husman, Meklin et al 2002), and with both allergic and non-allergic respiratory disease (Salvaggio 1981;Lehrer 1983;Licorish 1985;Flannigan 1994;Spengler 1994;Verhoeff 1995;Jarvis and Morey 2001) in several industrialized nations. Asthma was associated with 'damp houses and fenny countries' three centuries ago by Sir John Floyer (Sakula 1984).…”

Section: Causes Of Poor Iaq and Desiccation As An Iaq Control Strategymentioning

confidence: 99%

Improving the Quality of the Indoor Environment Utilizing Desiccant-Assisted Heating, Ventilating, and Air Conditioning Systems

Straus¹,

Larrañaga²,

Karunasena³

et al. 2011

Chemistry, Emission Control, Radioactive Pollution and Indoor Air Quality

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“…9 Positive bronchial challenges in individuals with positive skin-test results have been noted with Alternaria species, Basidiomycetes species, Cladosporium species, Penicillium species, and others. 10,11 A casecontrol study investigated 11 young patients with asthma who experienced respiratory arrest (2 fatal cases) in seasons when high levels of Alternaria spores are present. Of the 11 patients, 10 had positive Alternaria skin-test results, compared with 31% of the controls, suggesting that Alternaria exposure was a risk factor for respiratory arrest.…”

Section: Asthmamentioning

confidence: 99%

Spectrum of Noninfectious Health Effects From Molds

Mazur¹,

Kim²

2006

Pediatrics

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Molds are multicellular fungi that are ubiquitous in outdoor and indoor environments. For humans, they are both beneficial (for the production of antimicrobial agents, chemotherapeutic agents, and vitamins) and detrimental. Exposure to mold can occur through inhalation, ingestion, and touching moldy surfaces. Adverse health effects may occur through allergic, infectious, irritant, or toxic processes. The cause-and-effect relationship between mold exposure and allergic and infectious illnesses is well known. Exposures to toxins via the gastrointestinal tract also are well described. However, the cause-and-effect relationship between inhalational exposure to mold toxins and other untoward health effects (eg, acute idiopathic pulmonary hemorrhage in infants and other illnesses and health complaints) is controversial and requires additional investigation. In this report we examine evidence of fungal-related illnesses and the unique aspects of mold exposure to children. Mold-remediation procedures are also discussed. BACKGROUND

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Role of and spores in the pathogenesis of asthma

Cited by 181 publications

References 21 publications

The Effect of Outdoor Fungal Spore Concentrations on Daily Asthma Severity

The Effect of Outdoor Fungal Spore Concentrations on Daily Asthma Severity

Improving the Quality of the Indoor Environment Utilizing Desiccant-Assisted Heating, Ventilating, and Air Conditioning Systems

Spectrum of Noninfectious Health Effects From Molds

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