Role of Alpha-Fetoprotein in the Pathogenesis of Cancer
Alok Ghosh Chaudhuri,
Saptadip Samanta,
Monalisha Dey
et al.
Abstract:Alpha-fetoprotein (AFP) belongs to the albuminoid protein family and is considered as the fetal analog of serum albumin. This plasma protein is initially synthesized in the fetal liver and yolk sac and shows a maximum peak near the end of the first trimester. Later, concentrations begin to decline prenatally and drop precipitously after birth. This protein has three key ligand-binding pockets for interactions with various biomolecules. It contains multiple phosphorylation and acetylation sites for the regulati… Show more
Biotin-functionalized nanoparticles enhance cancer detection by targeting biotin receptors, which are overexpressed on cancer cells. This targeted approach improves imaging accuracy and efficacy in identifying cancerous tissues.
Biotin-functionalized nanoparticles enhance cancer detection by targeting biotin receptors, which are overexpressed on cancer cells. This targeted approach improves imaging accuracy and efficacy in identifying cancerous tissues.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.