Role of Acute Hepatitis E Virus Super Infection in Progression Stage of Liver Cirrhosis

Abstract

Background: Despite acute hepatitis E virus (HEV) infection is a self-limiting acute infection, it could be a cause of acute on top of chronic liver failure (ACLF) in patients with chronic liver disease. Thus, identification role of HEV superinfection in deterioration of liver cirrhosis with early treatment could save life of those patients. Aim: To determine the percentage and the role of HEV infection in order to detect outcomes of patients with ACLF, to find effect of HEV infection on liver, kidney functions and coagulation profile, and to find specific clinical or laboratory characteristics of these patients if present.