Role of a perhydroxyl radical in the chelator-mediated Fenton reaction

Abstract

The chelator-mediated Fenton (CMF) chemistry is one of the main biological non-enzymatic systems for oxygen-centered radical generation. Perhydroxyl radical (HO2•) is a secondary radical specie in CMF systems, however, despite...

Characterizations and molecular docking mechanism of the interactions between peptide FDGDF (Phe-Asp-Gly-Asp-Phe) and SOD enzyme

“…Unlike DPPH, ·OH is the most potent free radical and can react with the most active peptides. ·OH boasts a high reduction potential, and some antioxidants with substantial electron transfer capability can neutralize ·OH [ 42 ]. In this study, the scavenging rate of ·OH free radicals increased from Days 0–10, but a significant increase was observed from Days 10–47.…”

Water-Soluble Alkali Lignin as a Natural Radical Scavenger and Anticancer Alternative

“…The improved ferric-ion-reducing potential of lignin aqueous solutions after UV-B irradiation resembles a natural plant-like mechanism of lignin degradation by brown rot fungi, which represents a non-enzymatic oxidation process (Fenton-like reaction) [ 48 , 49 ]. But the critical factor to keep a Fenton system active is making Fe 2+ available, because its concentration is usually low in natural environments [ 50 , 51 ]. The possible explanation for the upgraded FRAP activity of UV-B-irradiated alkali lignin aqueous solutions, is represented in Scheme 3 .…”