Abstract:THE ROLE OF THE PINEAL GLAND IN THE REGULATION OF THE HYPOTHALAMO-PITUITARY-TESTI-CULAR AXIS. The role of the pineal gland and of its main hormone, melatonin, has not yet been clearly defined. The best known activity of the gland is antigonadal, at least in the experimental animals. In fact, the administration of melatonin or the modification of the light/darkness ratio, that is considered the most important regulatory mechanism of the melatonin-synthetic activity, leads to a gonadal regression by which all th… Show more
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