Rola badania PET w leczeniu raka szyjki macicy w doniesieniach na 3rd ESTRO Forum 2015

Burchardt, Ewa

doi:10.21641/los.14.2.28

Cited by 1 publication

(1 citation statement)

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“…The evaluation of cervical cancer progression is very important to prepare an optimal treatment plan. According Burchardt et al [7], in up to 30% of patients with cervical cancer the PET/CT may change the original therapeutic plan of radio/radiochemotherapy and surgical treatment. The aim of the study was to compare the diagnostic value of the preoperative evaluation using the 18 F-FDG-PET-CT with a histopathological examination of the lymph nodes removed during radical hysterectomy and pelvic lymph node dissection in patients with cervical cancer.…”

Section: Introductionmentioning

confidence: 99%

Comparison of positron emission tomography with computed tomography examination with histopathological assessment of pelvic lymph nodes in patients with cervical cancer treated surgically

Kaźmierczak

Cholewiński

Nowakowski

2021

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According to the literature, fluor-18-fluorodeoxyglucose positron emission tomography with computed tomography ( 18 F-FDG-PET-CT) is the most effective technique for the examination and detection of metastases in the lymph nodes in patients with cervical cancer. This study aimed to compare the diagnostic value of the preoperative evaluation using 18 F-FDG-PET-CT with a histopathological examination of the lymph nodes removed during radical hysterectomy and pelvic lymph node dissection in patients with cervical cancer. Material and methods: Retrospective analysis covered the medical records of 42 patients with cervical cancer (stage IA-IB according to International Federation of Gynaecology and Obstetrics 2009) treated with radical Piver type III hysterectomy and pelvic lymph node dissection. The preoperative diagnosis was made using a PET/CT examination. Results: The result of the 18 F-FDG-PET-CT examination highlighted a suspicion of lymph node metastases in 13 patients (31%). The histopathological examination confirmed this in 12 patients (29%). Metastatic lymph nodes were correctly diagnosed using 18 F-FDG-PET-CT in 8 out of the 12 cases confirmed by the histopathological examination. In the patient-based study, sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 66.8%, 83.3%, 61.5%, 86.2 % and 78.6%, respectively. Conclusions: We confirmed the usefulness of PET in the preoperative assessment of cervical cancer advancement, especially in correlation with the new 2018 International Federation of Gynaecology and Obstetrics staging system.

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Section: Introductionmentioning

confidence: 99%