Roentgenographic Features of Thymolipoma

Teplick, J. George; Nedwich, Alexander; Haskin, Marvin E.

doi:10.2214/ajr.117.4.873

Cited by 56 publications

(30 citation statements)

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“…15 Differential diagnosis with large pleural tumor, basal atelectasis, and pulmonary sequestration is necessary. 3 Chest skiagram of our case showed a large homogenous density lesion in right hemithorax. Characteristic CT findings involve fatty tissue containing soft tissue streaks that probably represent islands of normal thymic components.…”

Section: Discussionsupporting

confidence: 46%

“…3 Pathogenesis of this tumour has not been clearly elucidated, four possible theories have been postulated. Briefly, the first suggests that thymolipomas are lipomas arising from within the thymus 6. The second is that the thymus initially undergoes hyperplasia, the gland itself thereafter becoming replaced by fatty tissue.…”

Section: Discussionmentioning

confidence: 99%

“…2 It accounts for 2% to 9% of thymic tumours. 3 We report a case of thymolipoma in a 37 years old male patient, who presented with cough, dyspnea, chest pain for 2 months. CT THORAX revealed a large anterior mediastinal mass extending in to right hemithorax arising from thymus gland, with multiple areas of fat density, no significant mediastinal adenopathy, complete collapse of right middle and lower lobe suggestive of thymolipoma.…”

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confidence: 96%

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Thymolipoma: A Rare, Large Anterior Mediastinal Mass

Premananth¹,

Thangaswamy²,

Baby³

et al. 2015

jemds

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Thymolipoma is a rare benign tumor of anterior mediastinum, described by Lange in 1916. 1 Less than 200 cases have been reported worldwide. 2 It accounts for 2% to 9% of thymic tumours. 3 We report a case of thymolipoma in a 37 years old male patient, who presented with cough, dyspnea, chest pain for 2 months. CT THORAX revealed a large anterior mediastinal mass extending in to right hemithorax arising from thymus gland, with multiple areas of fat density, no significant mediastinal adenopathy, complete collapse of right middle and lower lobe suggestive of thymolipoma. CT guided biopsy suggestive of thymic neoplasm. The tumour was removed enbloc through surgery. Histopathological examination of large mass lesion confirmed thymolipoma. We report this case to emphasize the importance of considering thymolipoma as a differential diagnosis of anterior mediastinal mass, although rare.

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Section: Discussionsupporting

confidence: 46%

Section: Discussionmentioning

confidence: 99%

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confidence: 96%

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Thymolipoma: A Rare, Large Anterior Mediastinal Mass

Premananth¹,

Thangaswamy²,

Baby³

et al. 2015

jemds

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“…They were first described by Hall in 1948 in a study on tumors composed of fat and thymic cells 2 . They represent 2 to 9% of all thymic neoplasias, and, up to 1950, only approximately 50 cases had been reported 3 . In recent years, no update on the exact number of current cases has been published, but with the improvement in diagnostic methods and the relative ease of access to medical services, this number is believed to be considerably greater.…”

Section: Discussionmentioning

confidence: 99%

“…They are usually large and may become huge masses. In 68% of the cases published, these tumors weighed more than 500 g, and, in 23% of the cases, they exceeded 2,000 g. The largest tumor described weighed more than 12,000 g 3,10 .…”

Section: Case Reportmentioning

confidence: 93%

Dor torácica por compressão atrial direita por timolipoma

Filho¹,

Melo²,

Macedo³

et al. 2004

Arq. Bras. Cardiol.

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484On physical examination, the patient was hydrated, acyanotic, anicteric, eupneic, afebrile, with healthy coloring, in regular general condition, and had neither jugular venous distension nor peripheral edema. His blood pressure was 140/100 mmHg and his heart rate was 120 bpm. His pulses were palpable, symmetric, rhythmic, with no changes in peripheral perfusion. The ictus cordis was located on the fifth left intercostal space, at the level of the left midclavicular line, and had approximately 2 digital pulps. The cardiac sounds had normal intensity and no cardiac murmur was heard. On pulmonary auscultation, the respiratory sounds were present bilaterally, and no rales were heard. The abdomen was flat, flaccid with hydro-aerial noises, not tender on palpation, and no visceromegaly was observed.The biochemical tests and electrocardiogram showed no changes. On chest radiography, a mild enlargement of the cardiac area was observed with an expanding lesion in the anteroinferior mediastinum, in continuity with the cardiac image ( fig.1). The esophagogram showed no signs of extrinsic compression of the esophagus. Upper digestive endoscopy showed only a mild enanthematous antral gastritis.Transthoracic echodopplercardiography showed a mild extrinsic compression of the anterolateral region of the right atrium. The transesophageal echocardiogram confirmed this compression with no significant hemodynamic repercussions, and the presence of a mild systolic reflux (escape) in the tricuspid valve ( fig. 2).To complement the investigation, the patient underwent chest computed tomography performed with 5-and 10-mm-thick axial sections after intravenous infusion of contrast medium. The tomography revealed the presence of an expanding lesion with a fat attenuation coefficient, regular and precise contours, located in the anterior mediastinum to the right, slightly deviating from the right atrium posteriorly. The lesion measured 12.0 x 7.4 x 9.6 cm and was suggestive of thymolipoma or pericardial lipoma ( fig. 3).With these hypotheses, the patient was referred for surgical treatment. Thoracotomy provided complete excision of the tumoral mass, which weighed approximately 580 g. No regional macroscopic metastases were evident, and later anatomicopathological examination confirmed the diagnosis of thymolipoma (fig. 4).

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Thymolipoma in association with myasthenia gravis

Otto

Löning

Lachenmayer

et al. 1982

Cancer

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Among 72 thymic tumors that were examined we have found five (7.5%) thymolipomas. Two of these patients have had clinical symptoms. One, a five‐year‐old boy, has had an erythrocyte hypoplasia as well as a hypogammaglobulinemia. The other patient, a 56‐year‐old man, has had myasthenia gravis. This case is the second in the world literature in which a thymolipoma is associated with symptoms of myasthenia gravis. The clinical, radiologic, and histopathologic findings and the pathogenesis of thymolipoma are discussed.

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Roentgenographic Features of Thymolipoma

Cited by 56 publications

References 0 publications

Thymolipoma: A Rare, Large Anterior Mediastinal Mass

Thymolipoma: A Rare, Large Anterior Mediastinal Mass

Dor torácica por compressão atrial direita por timolipoma

Thymolipoma in association with myasthenia gravis

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