Roentgen-Ray Treatment of the Spine in Lichen Planus

Driver, J R

doi:10.1001/archderm.1929.02380220089004

Cited by 6 publications

(2 citation statements)

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“…They utilized either direct irradiation methods on skin lesions (4, 7) or indirect methods aiming at the spine. In those days the concept of the involvement of the sympathetic nervous system in the physiopathogeny of LP was actually in vogue in France (5). Flare-ups of LP on RT-irradiated areas as well as LP generalization were then observed (6,8).…”

Section: Discussionmentioning

confidence: 99%

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Radiation-associated lichen planus: a case report and literature review

Kluger¹

2017

Acta Dermatovenerologica Alpina Pannonica Et Adriatica

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Percutaneous radiotherapy (RT) may cause a range of acute and chronic cutaneous side-effects on irradiated areas. Localized or generalized lichen planus (LP) has occasionally been reported after RT. The mechanisms of LP are unclear. A case report and a systematic review of the literature were performed. Including the present case, 12 cases of LP have been reviewed in association with oncologic radiotherapy since 2002. Of these, 83% of patients developed LP after RT. LP occurred with a median delay of 30.7 days after RT completion and a median dose of 50 Gy. LP is a rare complication during RT that mainly occurs at the site of radiation and can sometimes spread and become generalized. Its physiopathogeny remains unclear. In some cases, patients may have preexisting but asymptomatic LP before RT. RT would therefore act as an indicator of the disease. The treatment of RT-associated LP is similar to that for any LP.

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Section: Discussionmentioning

confidence: 99%

“…At the beginning of the twentieth century, RT was a popular treatment for cutaneous LP, especially in France (4,5). At the time, the occurrence of LP lesions on RT areas as well as flare-ups of the disease had been well documented (6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%