“…A delay in oesophageal transit time when the subject is in the recumbent position, and inability to swallow against gravity, were observed radiologically in systemic sclerosis by Kure, Yamagata, Tsukada, and Hiyoshi (1936), Lindsay, Templeton, and Rothman (1943), Hale and Schatzki (1944), Olsen, O'Leary, and Kirklin (1945), Mahrer, Evans, and Steinberg (1954), and Boyd, Patrick, and Reeves (1954). The manometric studies of Kramer and Ingelfinger (1949) and of Dornhorst, Pierce, and Whimster (1954) confirmed the impairment or complete absence of oesophageal peristalsis in many patients with systemic sclerosis.…”