Abstract:Misfolded peptide amyloid beta (Aβ 42 ), neuro brillary tangles of hyper-phosphorylated tau, oxidative damage to the brain, neuroin ammation are distinguished determinants of Alzheimer's disease (AD) responsible for disease progression. This multifaceted neurodegenerative disease is challenging to cure under a single treatment regime until the key disease-determinants are traced for their sequential occurrence in disease progression. In an early report, a novel side-chain tripeptide containing PEGylated block … Show more
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