Robust ultrasensitive stretchable sensor for wearable and high-end robotics applications

Ahmed, Faheem; Soomro, Afaque Manzoor; Ashraf, Hina; Rahim, Abdul; Asif, Arun; Jawed, Bushra; Waqas, Muhammad; Choi, Kyung Hyun

doi:10.1007/s10854-022-09324-0

Cited by 12 publications

(6 citation statements)

References 67 publications

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“…For example, researchers can construct Noninvasively harvest culture fluid/ cells from in vitro organ models directly on the sensor surface for further detection or the capture of high-resolution photographs The capacity to link and connect modular multiorganon-a-chip systems disconnecting the organ modules and sensor systems allows the gadgets' long-term functionality by eliminating the chips that aren't working. Researchers in integrated MPS require real-time system status information [81,82]. Physical parameters with short sample-to-answer times, such as temperature, pH, and oxygen, make this simple.…”

Section: Discussionmentioning

confidence: 99%

A Comprehensive Review of Biosensor Integration in Microphysiological Systems for Online Monitoring: Current Challenges and Future Advancements

et al. 2023

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The goal of microphysiological systems (MPS) is to replicate the relevant functionality of human organ tissues in in vitro. MPS technology so far has been used to simulate the various human organs and with the help of sensor integration in the MPS systems the biological activities of the organ to be modeled have been translated into data to be analyzed for further considerations. Most standard characterization approaches are intrusive and detrimental, and not feasible for online monitoring of cell cultures. Microfluidic biosensors, for instant, provide non‐invasive on‐line detection of biomarkers and molecules under targeted indicators with a high detection extent, successfully overcoming the limits of existing approaches. Microfluidic biosensors are rapidly being incorporated into MPS and employed for real‐time target identification as a result. In this review the focus is on emerging ways for miniaturizing and embedding biosensing systems in MPS also known as “organ‐on‐chip”. Cutting‐edge microfluidic biosensors are also covered with examples, showing their key benefits in monitoring MPS and highlighting current breakthroughs, before describing the remaining problems and anticipated future improvements in integrated microfluidic biosensors.

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Section: Discussionmentioning

confidence: 99%

A Comprehensive Review of Biosensor Integration in Microphysiological Systems for Online Monitoring: Current Challenges and Future Advancements

et al. 2023

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“…Similarly, surface tension and wettability can impact the adhesion and migration of cells within microfluidic devices, which is important for studying processes such as angiogenesis and tumor metastasis ( Tovar-Lopez et al, 2019 ; Kausar et al, 2021 ; Farooqi et al, 2022 ; Kausar et al, 2022 ). These parameters enable the selection of appropriate materials, cell types, and culture conditions to ensure optimal organ functionality and accurate disease modeling ( Ahmed et al, 2022a ; Ahmed, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery

et al. 2023

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The inefficiency of existing animal models to precisely predict human pharmacological effects is the root reason for drug development failure. Microphysiological system/organ-on-a-chip technology (organ-on-a-chip platform) is a microfluidic device cultured with human living cells under specific organ shear stress which can faithfully replicate human organ-body level pathophysiology. This emerging organ-on-chip platform can be a remarkable alternative for animal models with a broad range of purposes in drug testing and precision medicine. Here, we review the parameters employed in using organ on chip platform as a plot mimic diseases, genetic disorders, drug toxicity effects in different organs, biomarker identification, and drug discoveries. Additionally, we address the current challenges of the organ-on-chip platform that should be overcome to be accepted by drug regulatory agencies and pharmaceutical industries. Moreover, we highlight the future direction of the organ-on-chip platform parameters for enhancing and accelerating drug discoveries and personalized medicine.

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“…As a result, the sensor became stiff and its elongation was limited. As the example of a liquid-type sensor, wearable sensors including skin sensors based on glycerol and graphene quantum dots (Gly-GQDs) as sensing units were proposed (Ahmed et al, 2022). In addition, a fluidic strain sensor based on a biocompatible conductive poly (3, 4ethylenedioxythiophene) polystyrene sulfonate multiwall carbon nanotube (PEDOT:PSS/MWCNT) liquid was also proposed (Jabbar et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Excellent Miniature Thin Film Dielectric Elastomer Sensors for Robot Fingers Used in Human-Robot Interaction

Chiba,

Waki

2023

AAES

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Traditional sensors used to measure properties such as deformation and pressure often use materials such as metals, ceramics, piezos and polymers. However, since many of these materials are hard, it can be difficult to measure them with a single sensor when the pressure or elongation applied to the object changes. In this experiment, a dielectric elastomer thin-film pressure sensor (0.2 mm) was fabricated using hydrogenated nitrile rubber with significantly improved hardness and elongation. This single sensor can accurately measure pressure from 1gf to 20kgf. Also, the response speed was 50ms, which was sufficiently fast. A dielectric elastomer stretch sensor was also developed. This sensor uses elastic and flexible single-walled carbon nanotubes as dielectric elastomer electrodes for the hydrogenated nitrile rubber. This greatly improved the mechanical flexibility and stretchability of the stretch sensor, making it possible to operate it as a sensor even at 400% elongation. By attaching this stretch sensor to the robot's finger closely, it is possible to detect the dynamic movement of the robot's finger and to detect the force (pressure) when the fingertip touches the target object with the above pressure sensor. In addition, by using the small diaphragm-type dielectric elastomer actuator, it was confirmed that the sensation of the robot's touching an object could be fed back to the human finger. As a result, it is thought that the feeling of the robot’s finger touching an object could be driven more realistically and accurately. In addition, both a dielectric elastomer stretch sensor and a dielectric elastomer pressure sensor were attached to the finger of the robot, and the movement of the human’s finger was sensed and the force (pressure) when the finger touched the object was also able to be detected.

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Robust ultrasensitive stretchable sensor for wearable and high-end robotics applications

Cited by 12 publications

References 67 publications

A Comprehensive Review of Biosensor Integration in Microphysiological Systems for Online Monitoring: Current Challenges and Future Advancements

A Comprehensive Review of Biosensor Integration in Microphysiological Systems for Online Monitoring: Current Challenges and Future Advancements

Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery

Excellent Miniature Thin Film Dielectric Elastomer Sensors for Robot Fingers Used in Human-Robot Interaction

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