Robust Synthesis of Size-Dispersal Triangular Silver Nanoprisms via Chemical Reduction Route and Their Cytotoxicity

Abstract

Triangular silver nanocrystals, well-known as nanoprisms (Ag-NPrs), were successfully developed via a robust and straightforward direct chemical reduction synthetic approach, producing desirable tiny and well-controlled Ag-NPrs. This procedure was accomplished by fabricating a mixture of di-sodium succinate hexa-hydrate (DSSH) and tri-sodium citrate di-hydrate (TSCD) as capping agents at optimal synthetic conditions and under an open-air condition, which proved to be an enormous challenge. Additionally, the Ag-NPrs were fully characterized by UV-vis spectra, X-ray diffraction (XRD), scanning electron microscope (SEM), and dynamic light scattering (DLS). Likewise, the formation stages from spherical silver nanoparticles (Ag-NPs) to triangular Ag-NPrs were also captured simultaneously via transmission electron microscope (TEM) and high-resolution transmission electron microscope (HR-TEM) images. More interestingly, an active thin silica-shell was efficiently applied on the Ag-NPrs outer-layer to increase their functionality. Furthermore, to confirm their biocompatibility, we also carried out cell viability assays for the Ag-NPs, Ag-NPrs, and Ag-NPrs@SiO2 with different concentrations at 62.5, 125, and 250 µg/mL after 12, 24, and 48 h of exposure time, respectively, on a regular African green monkey kidney cell line. The cell viability test results exemplified that the three silver nanostructures were toxic-free and suitable for further potential biological applications in the near future.

Biosynthesis of Silver Nanoparticles by Marine Actinobacterium Nocardiopsis dassonvillei and Exploring Their Therapeutic Potentials

“…For the synthesis of AgNPs, various physical and chemical methods such as microwave assistance, thermal decomposition, and chemical reduction have been employed. However, these conventional methods are energy intensive, use hazardous chemicals, are time consuming, and pose environmental and biological risks, precluding their therapeutic applications ( Otari et al, 2015 ; Bahlol et al, 2019 ; Khalil et al, 2021 ). On the other hand, biological methods are simple, quick, and inexpensive approaches to synthesize nanostructure materials as well as to reduce the generation of hazardous substances toxic to the environment and human health ( Singh et al, 2020 ; Nikzamir et al, 2021 ).…”

“…Microorganisms almost certainly contribute to the production of a large number of nucleation centers and to the establishment of conditions conducive to the formation of highly dispersed nanoparticle systems. In addition, microorganisms immobilize the particles and provide a viscous medium containing extracellular secreted enzymes to completely prevent or minimize the aggregation rate ( Bahlol et al, 2019 ). Several studies have been published on the use of bacteria such as Bacillus subtilis , as well as fungi such as Fusarium oxysporum , in the biosynthesis of AgNPs ( Hulkoti and Taranath, 2014 ).…”

Antibacterial Properties of Biodegradable Silver Nanoparticle Foils Based on Various Strains of Pathogenic Bacteria Isolated from the Oral Cavity of Cats, Dogs and Horses

“…Microscopic studies showed that depending on the reducer used, the obtained nanoparticles had different sizes and shapes. The shape of the nanoparticles has a strong influence on the optical and biological properties of the samples [ 36 , 37 ]. The used saccharides have different structures, which may explain the differences in reducing and capping ability.…”

The Effects of Nanosilver on Bacterial Contamination and Increase Durability Cultivars of Rosa hybrida L. Through of Stenting Method

“…The application of silver nanoparticles along with calcium in many cases has a better effect on the growth indices of cut flowers so that the use of silver nanoparticles in solutions that maintain cut flowers increases the shelf life of these flowers and calcium nanoparticles. They also delay the aging of plant tissues (33). Due to the fact that calcium plays a role in the structure and functions of cell membranes by binding proteins with enzymatic and non-enzymatic roles to cell membrane phospholipids, thus the activity of ethylene-producing enzymes, which have a protein structure and bind to cell membranes.…”