2014
DOI: 10.22237/jmasm/1398918480
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Robust Regression Analysis for Non-Normal Situations under Symmetric Distributions Arising In Medical Research

Abstract: In medical research, while carrying out regression analysis, it is usually assumed that the independent (covariates) and dependent (response) variables follow a multivariate normal distribution. In some situations, the covariates may not have normal distribution and instead may have some symmetric distribution. In such a situation, the estimation of the regression parameters using Tiku's Modified Maximum Likelihood (MML) method may be more appropriate. The method of estimating the parameters is discussed and t… Show more

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Cited by 4 publications
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“…It is obvious that the key to the use of MLE is the a priori determination of the type of probability distribution. Note that in addition to the EPD family, many different types of symmetric distributions are used to solve the problems of regression analysis: elliptical laws (logistic, Cauchy, Student t-distribution) [36][37][38], various Gaussian distributions [39,40]. In addition, there are specially developed models of symmetric distributions that make it possible to change the value of the excess coefficient and the severity of the tails of regression errors [41,42].…”
Section: Literature Review and Problem Statementmentioning
confidence: 99%
“…It is obvious that the key to the use of MLE is the a priori determination of the type of probability distribution. Note that in addition to the EPD family, many different types of symmetric distributions are used to solve the problems of regression analysis: elliptical laws (logistic, Cauchy, Student t-distribution) [36][37][38], various Gaussian distributions [39,40]. In addition, there are specially developed models of symmetric distributions that make it possible to change the value of the excess coefficient and the severity of the tails of regression errors [41,42].…”
Section: Literature Review and Problem Statementmentioning
confidence: 99%