Robust platform for inline Raman monitoring and control of perfusion cell culture
Boyong Wan,
Misaal Patel,
George Zhou
et al.
Abstract:Perfusion cell culture has been gaining increasing popularity for biologics manufacturing due to benefits such as smaller footprint, increased productivity, consistent product quality and manufacturing flexibility, cost savings, and so forth. Process Analytics Technologies tools are highly desirable for effective monitoring and control of long‐running perfusion processes. Raman has been widely investigated for monitoring and control of traditional fed batch cell culture process. However, implementation of Rama… Show more
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