“…In addition, the uncertainties present in the system as a result of technological factors and, economical factors as well as the uncertainty in the mathematical model and parameters employed to perform the optimization task pose severe challenges. A number of publications concerning optimization under uncertainty are available, covering a range of topics, such as process synthesis, design and control under uncertainty (Acevedo & Pistikopoulos (1996); Pintarič & Kravanja (2008); Ricardez-Sandoval, Douglas, & Budman (2011)), planning under uncertainty (Hansen, Grunow, & Gani, 2011), uncertainty on scheduling (Wang & Rong, 2010), strategic and global supply chain networks (Verderame & Floudas (2011); You & Grossmann (2008)), etc. Most of those publications, when addressing the uncertainty of the optimization problem, have focused on the operational parameters and external sources of uncertainties, for example, product demand and uncertainty on raw material availability.…”