We obtain sharp gradient bounds for perturbed di¤usion semigroups. In contrast with existing results, the perturbation is here random and the bounds obtained are pathwise. Our approach builds on the classical work of Kusuoka and Stroock [12,14,15,16], and extends their program developed for the heat semi-group to solutions of stochastic partial di¤erential equations. The work is motivated by and applied to nonlinear …ltering. The analysis allows us to derive pathwise gradient bounds for the un-normalised conditional distribution of a partially observed signal. It uses a pathwise representation of the perturbed semigroup following Ocone [21]. The estimates we derive have sharp small time asymptotics.MSC 2010: 60H30 (60G35; 60H35; 93E11).