Robust Control for Cancer Chemotherapy Through Time Delayed Estimation Philosophy
Rajasree Sarkar,
Oumaima Saidani,
Latifah Almuqren
et al.
Abstract:Chemotherapy, a vital cancer treatment, operates by delivering drugs to target and eliminate cancer cells in the patient body. Mathematical models like the log-kill, Norton-Simon, and E max hypotheses describe the growth/shrinking of the cancerous tumor due to the interaction and administration of the drugs with the tumor. This paper proposes a robust control approach based on artificial time-delayed theory to track the desired rate of change in tumor volume under model uncertainties and disturbances. The prop… Show more
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