Abstract:Highlights• Generalizes hierarchical population model to various distribution assumptions • Provides framework for efficient calibration of the hierarchical population model• Simulation study and application to experimental data reveal improved robustness and optimization performance
AbstractCellular heterogeneity is known to have important effects on signal processing and cellular decision making. To understand these processes, multiple classes of mathematical models have been introduced. The hierarchical pop… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.