Robust Association Between Inflammatory Bowel Disease and Generalized Anxiety Disorder

Fuller‐Thomson, Esme; Lateef, Rusan; Sulman, Joanne

doi:10.1097/mib.0000000000000518

Cited by 56 publications

(56 citation statements)

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“…The debilitating symptoms and complications of IBD often affect the patients' physical, mental and social well-being, resulting in an impaired quality of life (QoL) compared to the general population [3]. The diagnosis of IBD can be stressful and often causes psychological problems, such as feelings of hostility, despair, denial, sadness, grief and anxiety [4][5], which can induce long-term psychosocial impairments and negatively affect overall QoL [6][7]. Furthermore, the uncertainty of the disease course makes it challenging for patients to make decisions regarding their work and daily activities, which may result in unemployment or social isolation [6,[8][9].…”

Section: Introductionmentioning

confidence: 99%

Illness Perceptions and Outcomes in Patients with Inflammatory Bowel Disease: Is Coping a Mediator?

et al. 2016

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Purpose: Patients with inflammatory bowel disease (IBD) often experience severe impairment in different life domains. Psychological factors, such as illness perceptions and coping, may play a role in the adjustment to IBD as indicated by mental and physical health, activity and work impairment. The present study aimed at examining the assumption of the Common Sense Model (CSM) that coping mediates the relationship between illness perceptions and adjustment in patients with IBD. Method:In a cross-sectional design, 211 IBD patients (73% Crohn's disease, 40% male, mean age 42.9±12.9 years) attending an outpatient clinic completed questionnaires assessing illness perceptions (IPQ-R), coping (CORS), mental and physical health (SF-36) as well as activity and work impairment (WPAI). Multiple mediation analyses were applied that allow estimating the total and direct effects of all illness perception dimensions and the indirect effects through all coping strategies on the illness outcomes simultaneously. Results:The analyses yielded significant direct effects of perceptions regarding the cyclical course, the chronic course, the severity of the consequences, the comprehensibility, and the emotional impact of IBD on study outcomes. Additionally, significant indirect effects were found for the perceptions regarding the severity of the consequences, the possibility of personal control, and the comprehensibility of IBD on mental and physical health as well as activity impairment through the use of one specific coping strategy, i.e., reduction of activity. Conclusions:The results provide evidence for the assumptions of the CSM and suggest the importance of addressing illness perceptions and activity stimulation in quality health care for IBD patients.

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Section: Introductionmentioning

confidence: 99%

Illness Perceptions and Outcomes in Patients with Inflammatory Bowel Disease: Is Coping a Mediator?

et al. 2016

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“…Depressive and anxiety disorders are more frequent in patients diagnosed with IBD than in the main population [12,18]. The literature shows evidence of significant association between the activity of the disease and the occurrence of depressive symptoms and anxiety.…”

Section: Discussionmentioning

confidence: 99%

“…In this group, the factors that correlated most with anxiety were: chronic pain, female sex, and childhood sexual abuse [18]. Wider prevalence was observed during clinical exacerbation of IBD (80%) in comparison to remission (29%) [19].…”

Section: Introductionmentioning

confidence: 94%

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Depressive and anxiety symptoms among patients with inflammatory bowel diseases

Bielińska

Liebert

Lesiewska

et al. 2017

Medical Research Journal

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Depressive and anxiety symptoms among patients with inflammatory bowel diseases ABSTRACT Introduction. This study was conducted on a population of patients with inflammatory bowel disease (IBD) and was based on an assessment of the prevalence and severity of depression and anxiety symptoms in various clinical aspects. The psychological features of IBD patients are very important in the perception of symptoms, but crucial as triggers of IBD or as a releasing factor for IBD symptoms recurrence.Methods. The study included 130 patients with IBD, including 68 with Crohn's disease (CD) and 62 with ulcerative colitis (UC). The severity of anxiety and depression symptoms were examined by the Hospital Anxiety and Depression Scale (HADS). Patients were also subjected to assessment of anthropometric attributes, clinical factors, quality of life, and symptoms of the disease, with dedicated clinical scales.Results. The occurrence of significant symptoms of anxiety was estimated at 45.5% in patients with CD and 30.5% in the UC patients. Significant depressive symptoms related to 20.5% of people with CD and 17.5% of patients with UC. The parameters of anxiety and depression showed significant associations with parameters of quality of life, BMI, and the scales describing the exacerbation of the diseases.Conclusions. The analyses did not reveal significant differences in the severity and prevalence of symptoms of anxiety and depression in subgroups with IBD. The expansion of relevant symptoms of anxiety and depression in this population was greater than in the general population. In addition, there was a significant correlation between parameters of HADS and clinical factors.

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“…[1][2][3] Anxiety is even more prevalent with rates of approximately 30% in the IBD population. 4 Rates of both anxiety and depression have been reported to be even higher during periods of disease flares. 5 Psychiatric comorbidity influences the clinical manifestations of IBD, the overall functioning and wellbeing of patients, and may correlate with disease course.…”

mentioning

confidence: 99%

Empirically Supported Use of Psychiatric Medications in Adolescents and Adults with IBD

Thorkelson

Bielefeldt

Szigethy

2016

Inflammatory Bowel Diseases

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Antidepressant medications are frequently prescribed for depression, anxiety disorders, and chronic pain syndromes, but overall support for their efficacy is modest at best. Psychological interventions have growing support for having much more robust effects without the side effects of antidepressants and should be considered first-line treatment or at least an adjunct to psychotropic medications for these conditions.

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Robust Association Between Inflammatory Bowel Disease and Generalized Anxiety Disorder

Cited by 56 publications

References 47 publications

Illness Perceptions and Outcomes in Patients with Inflammatory Bowel Disease: Is Coping a Mediator?

Illness Perceptions and Outcomes in Patients with Inflammatory Bowel Disease: Is Coping a Mediator?

Depressive and anxiety symptoms among patients with inflammatory bowel diseases

Empirically Supported Use of Psychiatric Medications in Adolescents and Adults with IBD

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