Robotic <i>vs</i>. Retropubic radical prostatectomy in prostate cancer: A systematic review and a meta-analysis update

Tang, Kun; Jiang, Kehua; Chen, Hongbo; Chen, Zhiqiang; Xu, Hua; Ye, Zhangqun

doi:10.18632/oncotarget.13332

Cited by 62 publications

(41 citation statements)

References 107 publications

(225 reference statements)

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“…After first being described by Menon et al [4] , RALP has now replaced open retropubic radical prostatectomy (RRP) and laparoscopic RP (LRP) in most modern healthcare systems [3] . Despite the lack of high-quality randomised controlled trials (RCTs) showing a benefit over open RRP [5] , there is an abundance of non-randomised data that have shown clear advantages for intraoperative blood loss, transfusion rates, duration of catheterisation, length of hospital stay (LOS), positive margins, potency, continence, and readmission rates [6] , [7] .…”

Section: Introductionmentioning

confidence: 99%

Expanding the indications of robotic surgery in urology: A systematic review of the literature

Pal

Koupparis

2018

Arab Journal of Urology

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ObjectivesTo evaluate the recent developments in robotic urological surgery, as the introduction of robotic technology has overcome many of the difficulties of pure laparoscopic surgery enabling surgeons to perform complex minimally invasive procedures with a shorter learning curve. Robot-assisted surgery (RAS) is now offered as the standard for various surgical procedures across multiple specialities.MethodsA systematic search of MEDLINE, PubMed and EMBASE databases was performed to identify studies evaluating robot-assisted simple prostatectomy, salvage radical prostatectomy, surgery for urolithiasis, distal ureteric reconstruction, retroperitoneal lymph node dissection, augmentation ileocystoplasty, and artificial urinary sphincter insertion. Article titles, abstracts, and full text manuscripts were screened to identify relevant studies, which then underwent data extraction and analysis.ResultsIn all, 72 studies evaluating the above techniques were identified. Almost all studies were retrospective single-arm case series. RAS appears to be associated with reduced morbidity, less blood loss, reduced length of stay, and comparable clinical outcomes in comparison to the corresponding open procedures, whilst having a shorter operative duration and learning curve compared to the equivalent laparoscopic techniques.ConclusionEmerging data demonstrate that the breadth and complexity of urological procedures performed using the da Vinci® platform (Intuitive Surgical Inc., Sunnyvale, CA, USA) is continually expanding. There is a gaining consensus that RAS is producing promising surgical results in a wide range of procedures. A major limitation of the current literature is the sparsity of comparative trials evaluating these procedures.

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Section: Introductionmentioning

confidence: 99%

Expanding the indications of robotic surgery in urology: A systematic review of the literature

Pal

Koupparis

2018

Arab Journal of Urology

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“…PRIME has been successfully validated and demonstrated across several research endeavors; the extraction and investigation of patient emotions and clinical factors [23,24], the comparative analysis of patient-reported outcomes for different treatment types [25], and the study of online social influences on patient behaviours, decisions and emotions from diagnosis to recovery [19]. Outcomes of PRIME were compared with outcomes of three clinical trials [26][27][28] to assess the reliability and the validity of using PRIME [23] (Detailed information regarding PRIME is provided in S1 Fig).…”

Section: Methodsmentioning

confidence: 99%

Can online support groups address psychological morbidity of cancer patients? An artificial intelligence based investigation of prostate cancer trajectories

et al. 2020

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Background Online Cancer Support Groups (OCSG) are becoming an increasingly vital source of information, experiences and empowerment for patients with cancer. Despite significant contributions to physical, psychological and emotional wellbeing of patients, OCSG are yet to be formally recognised and used in multidisciplinary cancer support programs. This study highlights the opportunity of using Artificial Intelligence (AI) in OCSG to address psychological morbidity, with supporting empirical evidence from prostate cancer (PCa) patients. Methods A validated framework of AI techniques and Natural Language Processing (NLP) methods, was used to investigate PCa patient activities based on conversations in ten international OCSG (18,496 patients-277,805 conversations). The specific focus was on activities that indicate psychological morbidity; the reasons for joining OCSG, deep emotions and the variation from joining through to milestones in the cancer trajectory. Comparative analyses were conducted using t-tests, One-way ANOVA and Tukey-Kramer post-hoc analysis. Findings PCa patients joined OCSG at four key phases of psychological distress; diagnosis, treatment, side-effects, and recurrence, the majority group was 'treatment' (61.72%). The four groups varied in expression of the intense emotional burden of cancer. The 'side-effects' group expressed increased negative emotions during the first month compared to other groups (p<0.01). A comparison of pre-treatment vs post-treatment emotions showed that

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“…С тех пор во многих исследованиях сообщалось об очень разных результатах: в метаанализе Танга и соавт. (2016) безрецидивная выживаемость после РАРП через 24 месяца после операции была статистически значимо лучше, чем у открытой операции [45]. Однако с учетом факторов риска, таких как стадия pT, значение ПСА сыворотки крови в предоперационном периоде и балл по шкале Глисона, статистически значимых различий в онкологических результатах пока не выявлено [46].…”

Section: сравнение медико-онкологических аспектов открытой и роботизиunclassified

“…Не только значительно лучшая видимость за счет оптики, не имеющая себе равных среди хирургических микроскопов, теоретически способствует базовой защите основных анатомических структур, но также огромная подвижность операционных рычагов, которые с 360° свободой движения также не имеют аналогов Оригинальные исследования у других методов. Эти факторы объясняют гораздо меньшую кровопотерю [45,50]. Конечно, данный факт, который был подтвержден во многих работах, достигается не только качеством технологии и опытом хирурга, но и является основной предпосылкой для лапароскопического доступа: перед установкой оборудования воздух должен вводиться в полость тела через троакар, вставленный в забрюшинное пространство, что обычно делает рабочее место оптимально доступным по отношению к петлям кишечника, направленным вверх.…”

Section: сравнение интраоперационных параметров открытой и роботизироunclassified

Radical Prostatectomy: from Open Surgery towards Robotic Laparoscopy

Виланд

Burger

Denzinger

et al. 2020

Kreativnaâ hirurgiâ i onkologiâ

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Radical prostatectomy was first performed more than 100 years ago and has since become the gold standard in treatment of localized prostate cancer. Open surgery has been almost entirely replaced by robotic operations referred to as robot-assisted radical prostatectomy (RARP). Th e article introduces the basics of this innovative standard of operative access and tackles medical and historical aspects, oncological, medical and economic management pros and contras of robotic aid over open radical prostatectomy. Surgical trauma in RARP is clearly less pronounced compared to open surgery due to a much earlier postoperative mobilisation and a faster rehabilitation of patients leading to a statistically significant reduction in the length of hospital stay after RARP. Along with advances in intracorporeal imaging with 16-fold optical magnification coupled with shorter urethral catheterisation, RARP facilitates an earlier start of pelvic floor exercises, which reduces postoperative incontinence and need for pain relievers. Th e already mentioned technical advantages of the robotic method hold value to both patient and surgeon by securing instant access for an experienced colleague without interrupting the surgery. Noteworthy, the increasing advancement of robotic systems across the globe is leading urologist surgeons to abandon open operations. A drawback of the robotic method is much higher economic costs. However, greater expenditures may pay off in the long run by shorter hospital stays, faster rehabilitation and fewer complications demanding extra management and care.

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Robotic vs. Retropubic radical prostatectomy in prostate cancer: A systematic review and a meta-analysis update

Cited by 62 publications

References 107 publications

Expanding the indications of robotic surgery in urology: A systematic review of the literature

Expanding the indications of robotic surgery in urology: A systematic review of the literature

Can online support groups address psychological morbidity of cancer patients? An artificial intelligence based investigation of prostate cancer trajectories

Radical Prostatectomy: from Open Surgery towards Robotic Laparoscopy

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