Robot-assisted Radical Cystectomy with Totally Intracorporeal Urinary Diversion Versus Open Radical Cystectomy: 3-Year Outcomes from a Randomised Controlled Trial

Mastroianni, Riccardo; Tuderti, Gabriele; Ferriero, Mariaconsiglia; Anceschi, Umberto; Bove, Alfredo Maria; Brassetti, Aldo; D'Annunzio, Simone; Misuraca, Leonardo; Torregiani, Giulia; Covotta, Marco; Guaglianone, Salvatore; Gallucci, Michele; Simone, Giuseppe

doi:10.1016/j.eururo.2024.01.018

Cited by 12 publications

(2 citation statements)

References 28 publications

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“…In our cohorts, UD assessment were performed extracorporeally, which could have reduced the benefits of a totally robotic procedure [37]. Nonetheless, a recent RCT between ORC and RARC with a totally intracorporeal urinary reconstruction only showed similar oncological outcomes, but a significant impact on perioperative outcomes [41].…”

Section: Discussionmentioning

confidence: 99%

Assessing Trifecta and Pentafecta Success Rates between Robot-Assisted vs. Open Radical Cystectomy: A Propensity Score-Matched Analysis

Gavi,

Foschi,

Fettucciari

et al. 2024

Cancers

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Background: This study aimed to evaluate the surgical and oncological outcomes of robot-assisted radical cystectomy (RARC) versus open radical cystectomy (ORC) using trifecta and pentafecta parameters. Methods: The clinical data of 41 patients who underwent RARC between 2018 and 2022 were prospectively collected and retrospectively compared to those of 330 patients undergoing ORC using 1:1 propensity score matching. Trifecta was defined as simultaneous negative surgical margins (SMs), a lymph node (LN) yield ≥ 16, and the absence of major complications (Clavien–Dindo grade III–V) within 90 days postoperatively. Pentafecta additionally included a 12-month recurrence-free rate and a time between the transurethral resection of a bladder tumor (TURBT) and radical cystectomy (RC) ≤ 3 months. The continuous variables were compared using the Mann–Whitney U test, and the categorical variables were analyzed using the chi-squared test. Results: No statistically significant differences in trifecta and pentafecta success rates were observed between the RARC and ORC cohorts after propensity score matching. However, the RARC group exhibited significantly reduced blood loss (RARC: 317 mL vs. ORC: 525 mL, p = 0.01). Conclusions: RARC offers distinct advantages over ORC in terms of reduced blood loss, while trifecta and pentafecta success rates do not differ significantly between the two surgical approaches.

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Section: Discussionmentioning

confidence: 99%

Assessing Trifecta and Pentafecta Success Rates between Robot-Assisted vs. Open Radical Cystectomy: A Propensity Score-Matched Analysis

Gavi,

Foschi,

Fettucciari

et al. 2024

Cancers

View full text Add to dashboard Cite

show abstract

“…Indeed, UD choice also has a negligible impact on long-term oncologic outcomes in minimally invasive surgery. 3 In a multi-center study on RARC, disease stage and positive surgical margins were recognized as predictors of survival outcomes. 4 Therefore, the type of UD should not have an impact on oncologic outcomes.…”

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confidence: 99%