“…HIFU has been used for ablating several different types of cancer, including pancreas, bone, breast, liver, soft tissue and others. Within urological oncology, transrectal HIFU ablation of prostate cancer has been used extensively in Europe; in addition, a few studies have shown proof‐of‐concept for lap‐HIFU ablation of small renal masses . Herein, we explore the concept, and determine the technical feasibility of targeted ablation of the intact bladder wall and tumor using a lap‐HIFU approach in the human cadaver and live large animal model.…”