Robertsonian chromosomal variation and identification of metacentric chromosomes in feral mice

Gropp, A.; Winking, Heinz; Zech, L.; Müller, Hansjakob

doi:10.1007/bf00290787

Cited by 153 publications

(77 citation statements)

References 29 publications

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“…The overwhelmingly abundant appearance of centric fusion in man (e.g., Borgaonkar, 1984) and mouse (Gropp et al, 1972;Capanna et al, 1976) seems to provide the most strong supporting evidence for the fusion hypothesis.…”

Section: Introductionmentioning

confidence: 96%

Theoretical bases for karyotype evolution. II. The fusion burst in man and mouse.

Imai

Takahata

Maruyama

et al. 1988

The Japanese journal of genetics

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As a theoretical standard for evaluating the high incidence of centric fusion in man and mouse, the relative probabilities of occurrence of reciprocal translocation (Tr), inversion (In) and centric fusion (Fu) were estimated based on the randomcontact-and-exchange model. It was shown by this model that centric fusion was extremely rare (Fu=0.0002, In=0.0521 and Tr=0.9477 for a human haploid karyotype).On the other hand, the occurrence rate of centric fusion in human newborn babies and European feral mice was about 500-1,000 times higher than the theoretically expected values, which is termed here the "fusion burst". We suggest that the fusion burst may be induced by the physical proximity of telomeres on the nuclear membrane, and the exchange of DNA strands by errors of telomere replication mechanisms.The cytogenetical significance of the fusion burst is discussed with regard to the minimum interaction hypothesis proposed by Imai et al. (1986). We suggest two closely linked possibilities that (1) the fusion burst in man and mouse can theoretically be placed in karyotype evolution as a transitional phase in the main stream of the fission-inversion cycle, and (2) it may be accelerated by some unknown (mutagenic) factors other than ionizing radiation.

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Section: Introductionmentioning

confidence: 96%

Theoretical bases for karyotype evolution. II. The fusion burst in man and mouse.

Imai

Takahata

Maruyama

et al. 1988

The Japanese journal of genetics

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show abstract

“…Laboratory and wild mice carrying one or more such translocations have already been used to study evolutionary mechanisms and to observe the process and results of nondisjunction (Gropp et al 1972, White et al 1972a. The recent discovery of several of these mouse translocations suggests that periodic sampling of estab lished laboratory strains might demonstrate new translocations which could be used to further expand such studies.…”

Section: Resultsmentioning

confidence: 99%

AL/N: A Homozygous Robertsonian Translocation Mouse Strain Identical to <i>TlWh</i>

White

Tjio

1975

CYTOLOGIA

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“…In general, the relation ship may be explained then by a system of Robertsonian fusion as in other Arti odactyla and the presence of duplex centromeric C-bands further supports this as sumption. In mice, evolution associated with fusion produces biarmed chromosomes with a similar structure (Gropp and Winking 1972). On the other hand, the reduc tion of NF from 74 to 72 must be accomplished by other mechanisms, such as tandem fusion.…”

Section: Discussionmentioning

confidence: 99%

Centromeric Heterochromatin and G-Banding of the Red Brocket Deer, <i>Mazama americana temama</i> (Cervoidea, Artiodactyla) with a Probable Non-Robertsonian Translocation

Jorge¹,

Benirschke²

1977

CYTOLOGIA

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Robertsonian chromosomal variation and identification of metacentric chromosomes in feral mice

Cited by 153 publications

References 29 publications

Theoretical bases for karyotype evolution. II. The fusion burst in man and mouse.

Theoretical bases for karyotype evolution. II. The fusion burst in man and mouse.

AL/N: A Homozygous Robertsonian Translocation Mouse Strain Identical to <i>TlWh</i>

Centromeric Heterochromatin and G-Banding of the Red Brocket Deer, <i>Mazama americana temama</i> (Cervoidea, Artiodactyla) with a Probable Non-Robertsonian Translocation

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