Abstract:Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization.
Methods: Here, we sought to examine the roles of α-arrestins in the longevity of
Caenorhabditis elegans through an RNA interference screen.
Results: We found that knocking down each of 24 out of total 29
C. elegans α-arrestins had small or no effects on lifespan. Thus, individual
C. elegans α-arrestins may have minor effects on longevity.
Conclusions: This st… Show more
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